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Page 1
Short-term dietary changes can result in mucosal and systemic immune depression.
Siracusa F, Schaltenberg N, Kumar Y, Lesker TR, Steglich B, Liwinski T, Cortesi F, Frommann L, Diercks BP, Bönisch F, Fischer AW, Scognamiglio P, Pauly MJ, Casar C, Cohen Y, Pelczar P, Agalioti T, Delfs F, Worthmann A, Wahib R, Jagemann B, Mittrücker HW, Kretz O, Guse AH, Izbicki JR, Lassen KG, Strowig T, Schweizer M, Villablanca EJ, Elinav E, Huber S, Heeren J, Gagliani N. Siracusa F, et al. Among authors: guse ah. Nat Immunol. 2023 Sep;24(9):1473-1486. doi: 10.1038/s41590-023-01587-x. Epub 2023 Aug 14. Nat Immunol. 2023. PMID: 37580603 Free PMC article.
CD38: a NAADP degrading enzyme.
Schmid F, Bruhn S, Weber K, Mittrücker HW, Guse AH. Schmid F, et al. Among authors: guse ah. FEBS Lett. 2011 Nov 16;585(22):3544-8. doi: 10.1016/j.febslet.2011.10.017. Epub 2011 Oct 19. FEBS Lett. 2011. PMID: 22020217 Free article.
TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer.
Perez LG, Kempski J, McGee HM, Pelzcar P, Agalioti T, Giannou A, Konczalla L, Brockmann L, Wahib R, Xu H, Vesely MCA, Soukou S, Steglich B, Bedke T, Manthey C, Seiz O, Diercks BP, Gnafakis S, Guse AH, Perez D, Izbicki JR, Gagliani N, Flavell RA, Huber S. Perez LG, et al. Among authors: guse ah. Nat Commun. 2020 May 25;11(1):2608. doi: 10.1038/s41467-020-16363-w. Nat Commun. 2020. PMID: 32451418 Free PMC article.
IL22BP Mediates the Antitumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans.
Kempski J, Giannou AD, Riecken K, Zhao L, Steglich B, Lücke J, Garcia-Perez L, Karstens KF, Wöstemeier A, Nawrocki M, Pelczar P, Witkowski M, Nilsson S, Konczalla L, Shiri AM, Kempska J, Wahib R, Brockmann L, Huber P, Gnirck AC, Turner JE, Zazara DE, Arck PC, Stein A, Simon R, Daubmann A, Meiners J, Perez D, Strowig T, Koni P, Kruglov AA, Sauter G, Izbicki JR, Guse AH, Rösch T, Lohse AW, Flavell RA, Gagliani N, Huber S. Kempski J, et al. Among authors: guse ah. Gastroenterology. 2020 Oct;159(4):1417-1430.e3. doi: 10.1053/j.gastro.2020.06.033. Epub 2020 Jun 22. Gastroenterology. 2020. PMID: 32585307 Free PMC article.
CD38 downregulation modulates NAD+ and NADP(H) levels in thermogenic adipose tissues.
Benzi A, Sturla L, Heine M, Fischer AW, Spinelli S, Magnone M, Sociali G, Parodi A, Fenoglio D, Emionite L, Koch-Nolte F, Mittrücker HW, Guse AH, De Flora A, Zocchi E, Heeren J, Bruzzone S. Benzi A, et al. Among authors: guse ah. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Jan;1866(1):158819. doi: 10.1016/j.bbalip.2020.158819. Epub 2020 Sep 30. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 33010451
Publisher Correction: TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer.
Perez LG, Kempski J, McGee HM, Pelzcar P, Agalioti T, Giannou A, Konczalla L, Brockmann L, Wahib R, Xu H, Vesely MCA, Soukou S, Steglich B, Bedke T, Manthey C, Seiz O, Diercks BP, Gnafakis S, Guse AH, Perez D, Izbicki JR, Gagliani N, Flavell RA, Huber S. Perez LG, et al. Among authors: guse ah. Nat Commun. 2020 Nov 6;11(1):5740. doi: 10.1038/s41467-020-19685-x. Nat Commun. 2020. PMID: 33159069 Free PMC article.
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation.
Gu F, Krüger A, Roggenkamp HG, Alpers R, Lodygin D, Jaquet V, Möckl F, Hernandez C LC, Winterberg K, Bauche A, Rosche A, Grasberger H, Kao JY, Schetelig D, Werner R, Schröder K, Carty M, Bowie AG, Huber S, Meier C, Mittrücker HW, Heeren J, Krause KH, Flügel A, Diercks BP, Guse AH. Gu F, et al. Among authors: guse ah. Sci Signal. 2021 Nov 16;14(709):eabe3800. doi: 10.1126/scisignal.abe3800. Epub 2021 Nov 16. Sci Signal. 2021. PMID: 34784249
Role of CD38 in Adipose Tissue: Tuning Coenzyme Availability?
Benzi A, Grozio A, Spinelli S, Sturla L, Guse AH, De Flora A, Zocchi E, Heeren J, Bruzzone S. Benzi A, et al. Among authors: guse ah. Nutrients. 2021 Oct 23;13(11):3734. doi: 10.3390/nu13113734. Nutrients. 2021. PMID: 34835990 Free PMC article. Review.
TRPM2 Is Not Required for T-Cell Activation and Differentiation.
Lory NC, Nawrocki M, Corazza M, Schmid J, Schumacher V, Bedke T, Menzel S, Koch-Nolte F, Guse AH, Huber S, Mittrücker HW. Lory NC, et al. Among authors: guse ah. Front Immunol. 2022 Jan 14;12:778916. doi: 10.3389/fimmu.2021.778916. eCollection 2021. Front Immunol. 2022. PMID: 35095852 Free PMC article.
183 results