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Page 1
The NRF2-p97-NRF2 negative feedback loop.
Shakya A, Liu P, Godek J, McKee NW, Dodson M, Anandhan A, Ooi A, Garcia JGN, Costa M, Chapman E, Zhang DD. Shakya A, et al. Among authors: chapman e. Redox Biol. 2023 Sep;65:102839. doi: 10.1016/j.redox.2023.102839. Epub 2023 Aug 9. Redox Biol. 2023. PMID: 37573837 Free PMC article.
USP15 negatively regulates Nrf2 through deubiquitination of Keap1.
Villeneuve NF, Tian W, Wu T, Sun Z, Lau A, Chapman E, Fang D, Zhang DD. Villeneuve NF, et al. Among authors: chapman e. Mol Cell. 2013 Jul 11;51(1):68-79. doi: 10.1016/j.molcel.2013.04.022. Epub 2013 May 30. Mol Cell. 2013. PMID: 23727018 Free PMC article.
Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis.
Wu T, Zhao F, Gao B, Tan C, Yagishita N, Nakajima T, Wong PK, Chapman E, Fang D, Zhang DD. Wu T, et al. Among authors: chapman e. Genes Dev. 2014 Apr 1;28(7):708-22. doi: 10.1101/gad.238246.114. Epub 2014 Mar 17. Genes Dev. 2014. PMID: 24636985 Free PMC article.
Oncogenic KRAS confers chemoresistance by upregulating NRF2.
Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD. Tao S, et al. Among authors: chapman e. Cancer Res. 2014 Dec 15;74(24):7430-41. doi: 10.1158/0008-5472.CAN-14-1439. Epub 2014 Oct 22. Cancer Res. 2014. PMID: 25339352 Free PMC article.
Withaferin A Analogs That Target the AAA+ Chaperone p97.
Tao S, Tillotson J, Wijeratne EMK, Xu YM, Kang M, Wu T, Lau EC, Mesa C, Mason DJ, Brown RV, Clair JJ, Gunatilaka AAL, Zhang DD, Chapman E. Tao S, et al. Among authors: chapman e. ACS Chem Biol. 2015 Aug 21;10(8):1916-1924. doi: 10.1021/acschembio.5b00367. Epub 2015 Jun 3. ACS Chem Biol. 2015. PMID: 26006219 Free PMC article.
p62 links autophagy and Nrf2 signaling.
Jiang T, Harder B, Rojo de la Vega M, Wong PK, Chapman E, Zhang DD. Jiang T, et al. Among authors: chapman e. Free Radic Biol Med. 2015 Nov;88(Pt B):199-204. doi: 10.1016/j.freeradbiomed.2015.06.014. Epub 2015 Jun 24. Free Radic Biol Med. 2015. PMID: 26117325 Free PMC article. Review.
Role of Nrf2 and Autophagy in Acute Lung Injury.
Rojo de la Vega M, Dodson M, Gross C, Mansour HM, Lantz RC, Chapman E, Wang T, Black SM, Garcia JG, Zhang DD. Rojo de la Vega M, et al. Among authors: chapman e. Curr Pharmacol Rep. 2016 Apr;2(2):91-101. doi: 10.1007/s40495-016-0053-2. Epub 2016 Feb 6. Curr Pharmacol Rep. 2016. PMID: 27313980 Free PMC article.
861 results