Scheidt K - Search Results

1

NU-1223, a simplified analog of alstonine, with 5-HT_2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia.

Rajagopal L, Mahjour S, Huang M, Ryan CA, Elzokaky A, Csakai AJ, Orr MJ, Scheidt K, Meltzer HY. Rajagopal L, et al. Among authors: scheidt k. Behav Brain Res. 2023 Oct 2;454:114614. doi: 10.1016/j.bbr.2023.114614. Epub 2023 Aug 10. Behav Brain Res. 2023. PMID: 37572758

2

Enantioselective Syntheses of Heteroyohimbine Natural Products: A Unified Approach through Cooperative Catalysis.

Younai A, Zeng BS, Meltzer HY, Scheidt KA. Younai A, et al. Angew Chem Int Ed Engl. 2015 Jun 1;54(23):6900-4. doi: 10.1002/anie.201502011. Epub 2015 Apr 27. Angew Chem Int Ed Engl. 2015. PMID: 25914164

3

Discovery of Highly Potent Serotonin 5-HT₂ Receptor Agonists Inspired by Heteroyohimbine Natural Products.

Orr MJ, Cao AB, Wang CT, Gaisin A, Csakai A, Friswold AP, Meltzer HY, McCorvy JD, Scheidt KA. Orr MJ, et al. ACS Med Chem Lett. 2022 Mar 18;13(4):648-657. doi: 10.1021/acsmedchemlett.1c00694. eCollection 2022 Apr 14. ACS Med Chem Lett. 2022. PMID: 35450369 Free PMC article.

4

Rational Design of Highly Potent and Selective Covalent MAP2K7 Inhibitors.

Kim DR, Orr MJ, Kwong AJ, Deibler KK, Munshi HH, Bridges CS, Chen TJ, Zhang X, Lacorazza HD, Scheidt KA. Kim DR, et al. Among authors: scheidt ka. ACS Med Chem Lett. 2023 Apr 17;14(5):606-613. doi: 10.1021/acsmedchemlett.3c00029. eCollection 2023 May 11. ACS Med Chem Lett. 2023. PMID: 37197477 Free PMC article.

5

Synthesis and Structural Optimization of ATG4B Inhibitors for the Attenuation of Autophagy in Glioblastoma.

Kim DR, Orr MJ, Yu X, Munshi HH, Wang A, Trudeau C, Kwong AJ, Cheng SY, Scheidt KA. Kim DR, et al. Among authors: scheidt ka. ACS Med Chem Lett. 2024 Jan 16;15(2):258-264. doi: 10.1021/acsmedchemlett.3c00505. eCollection 2024 Feb 8. ACS Med Chem Lett. 2024. PMID: 38352843

6

Targeting the tamoxifen receptor within sodium channels to block osteoarthritic pain.

McCollum MM, Larmore M, Ishihara S, Ng LCT, Kimura LF, Guadarrama E, Ta MC, Vien TN, Frost GB, Scheidt KA, Miller RE, DeCaen PG. McCollum MM, et al. Cell Rep. 2022 Aug 23;40(8):111248. doi: 10.1016/j.celrep.2022.111248. Cell Rep. 2022. PMID: 36001977 Free PMC article.

7

Light-Driven Enantioselective Carbene-Catalyzed Radical-Radical Coupling.

Byun S, Hwang MU, Wise HR, Bay AV, Cheong PH, Scheidt KA. Byun S, et al. Angew Chem Int Ed Engl. 2023 Dec 4;62(49):e202312829. doi: 10.1002/anie.202312829. Epub 2023 Nov 6. Angew Chem Int Ed Engl. 2023. PMID: 37845183 Free PMC article.

8

Visible-light-induced coupling of carboxylic acids with alcohols/amines via a phosphorous linchpin strategy.

Peng Q, Gogoi AR, Rentería-Gómez Á, Gutierrez O, Scheidt KA. Peng Q, et al. Chem. 2023 Jul 13;9(7):1983-1993. doi: 10.1016/j.chempr.2023.04.011. Epub 2023 May 10. Chem. 2023. PMID: 37547627 Free PMC article.

9

Virtual High-Throughput Screening To Identify Novel Activin Antagonists.

Zhu J, Mishra RK, Schiltz GE, Makanji Y, Scheidt KA, Mazar AP, Woodruff TK. Zhu J, et al. Among authors: scheidt ka. J Med Chem. 2015 Jul 23;58(14):5637-48. doi: 10.1021/acs.jmedchem.5b00753. Epub 2015 Jul 7. J Med Chem. 2015. PMID: 26098096 Free PMC article.

10

Photocatalytic acyl azolium-promoted alkoxycarbonylation of trifluoroborates.

Zhu JL, Scheidt KA. Zhu JL, et al. Tetrahedron. 2021 Jul 16;92:132288. doi: 10.1016/j.tet.2021.132288. Epub 2021 Jun 16. Tetrahedron. 2021. PMID: 34262231 Free PMC article.

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