Byrne DP - Search Results

1

A peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanisms.

Cao M, Day AM, Galler M, Latimer HR, Byrne DP, Foy TW, Dwyer E, Bennett E, Palmer J, Morgan BA, Eyers PA, Veal EA. Cao M, et al. Among authors: byrne dp. Mol Cell. 2023 Sep 7;83(17):3140-3154.e7. doi: 10.1016/j.molcel.2023.07.018. Epub 2023 Aug 11. Mol Cell. 2023. PMID: 37572670 Free article.

2

Going for broke: targeting the human cancer pseudokinome.

Bailey FP, Byrne DP, McSkimming D, Kannan N, Eyers PA. Bailey FP, et al. Among authors: byrne dp. Biochem J. 2015 Jan 15;465(2):195-211. doi: 10.1042/BJ20141060. Biochem J. 2015. PMID: 25559089 Review.

3

The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner.

Bailey FP, Byrne DP, Oruganty K, Eyers CE, Novotny CJ, Shokat KM, Kannan N, Eyers PA. Bailey FP, et al. Among authors: byrne dp. Biochem J. 2015 Apr 1;467(1):47-62. doi: 10.1042/BJ20141441. Biochem J. 2015. PMID: 25583260 Free PMC article.

4

Tribbles pseudokinases: novel targets for chemical biology and drug discovery?

Foulkes DM, Byrne DP, Bailey FP, Eyers PA. Foulkes DM, et al. Among authors: byrne dp. Biochem Soc Trans. 2015 Oct;43(5):1095-103. doi: 10.1042/BST20150109. Biochem Soc Trans. 2015. PMID: 26517930 Review.

5

Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization.

Mohanty S, Oruganty K, Kwon A, Byrne DP, Ferries S, Ruan Z, Hanold LE, Katiyar S, Kennedy EJ, Eyers PA, Kannan N. Mohanty S, et al. Among authors: byrne dp. PLoS Genet. 2016 Feb 29;12(2):e1005885. doi: 10.1371/journal.pgen.1005885. eCollection 2016 Feb. PLoS Genet. 2016. PMID: 26925779 Free PMC article.

6

cAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometry.

Byrne DP, Vonderach M, Ferries S, Brownridge PJ, Eyers CE, Eyers PA. Byrne DP, et al. Biochem J. 2016 Oct 1;473(19):3159-75. doi: 10.1042/BCJ20160648. Epub 2016 Jul 21. Biochem J. 2016. PMID: 27444646 Free PMC article.

7

KinView: a visual comparative sequence analysis tool for integrated kinome research.

McSkimming DI, Dastgheib S, Baffi TR, Byrne DP, Ferries S, Scott ST, Newton AC, Eyers CE, Kochut KJ, Eyers PA, Kannan N. McSkimming DI, et al. Among authors: byrne dp. Mol Biosyst. 2016 Nov 15;12(12):3651-3665. doi: 10.1039/c6mb00466k. Mol Biosyst. 2016. PMID: 27731453 Free PMC article.

8

Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1).

Caron D, Byrne DP, Thebault P, Soulet D, Landry CR, Eyers PA, Elowe S. Caron D, et al. Among authors: byrne dp. Sci Signal. 2016 Dec 13;9(458):rs14. doi: 10.1126/scisignal.aah3525. Sci Signal. 2016. PMID: 27965426

9

DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis.

Milani M, Byrne DP, Greaves G, Butterworth M, Cohen GM, Eyers PA, Varadarajan S. Milani M, et al. Among authors: byrne dp. Cell Death Dis. 2017 Jan 12;8(1):e2552. doi: 10.1038/cddis.2016.485. Cell Death Dis. 2017. PMID: 28079887 Free PMC article.

10

Pseudokinases: update on their functions and evaluation as new drug targets.

Byrne DP, Foulkes DM, Eyers PA. Byrne DP, et al. Future Med Chem. 2017 Jan;9(2):245-265. doi: 10.4155/fmc-2016-0207. Epub 2017 Jan 18. Future Med Chem. 2017. PMID: 28097887 Review.

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