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Four additional natural 7-deazaguanine derivatives in phages and how to make them.
Cui L, Balamkundu S, Liu CF, Ye H, Hourihan J, Rausch A, Hauß C, Nilsson E, Hoetzinger M, Holmfeldt K, Zhang W, Martinez-Alvarez L, Peng X, Tremblay D, Moinau S, Solonenko N, Sullivan MB, Lee YJ, Mulholland A, Weigele PR, de Crécy-Lagard V, Dedon PC, Hutinet G. Cui L, et al. Nucleic Acids Res. 2023 Sep 22;51(17):9214-9226. doi: 10.1093/nar/gkad657. Nucleic Acids Res. 2023. PMID: 37572349 Free PMC article.
Novel genomic island modifies DNA with 7-deazaguanine derivatives.
Thiaville JJ, Kellner SM, Yuan Y, Hutinet G, Thiaville PC, Jumpathong W, Mohapatra S, Brochier-Armanet C, Letarov AV, Hillebrand R, Malik CK, Rizzo CJ, Dedon PC, de Crécy-Lagard V. Thiaville JJ, et al. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1452-9. doi: 10.1073/pnas.1518570113. Epub 2016 Feb 29. Proc Natl Acad Sci U S A. 2016. PMID: 26929322 Free PMC article.
Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens.
Yuan Y, Zallot R, Grove TL, Payan DJ, Martin-Verstraete I, Šepić S, Balamkundu S, Neelakandan R, Gadi VK, Liu CF, Swairjo MA, Dedon PC, Almo SC, Gerlt JA, de Crécy-Lagard V. Yuan Y, et al. Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):19126-19135. doi: 10.1073/pnas.1909604116. Epub 2019 Sep 3. Proc Natl Acad Sci U S A. 2019. PMID: 31481610 Free PMC article.
7-Deazaguanine modifications protect phage DNA from host restriction systems.
Hutinet G, Kot W, Cui L, Hillebrand R, Balamkundu S, Gnanakalai S, Neelakandan R, Carstens AB, Fa Lui C, Tremblay D, Jacobs-Sera D, Sassanfar M, Lee YJ, Weigele P, Moineau S, Hatfull GF, Dedon PC, Hansen LH, de Crécy-Lagard V. Hutinet G, et al. Nat Commun. 2019 Nov 29;10(1):5442. doi: 10.1038/s41467-019-13384-y. Nat Commun. 2019. PMID: 31784519 Free PMC article.
194 results