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Page 1
Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection.
Forde AJ, Kolter J, Zwicky P, Baasch S, Lohrmann F, Eckert M, Gres V, Lagies S, Gorka O, Rambold AS, Buescher JM, Kammerer B, Lachmann N, Prinz M, Groß O, Pearce EJ, Becher B, Henneke P. Forde AJ, et al. Among authors: gross o. Sci Immunol. 2023 Aug 18;8(86):eadg3517. doi: 10.1126/sciimmunol.adg3517. Epub 2023 Aug 11. Sci Immunol. 2023. PMID: 37566679
Walking over the inflammasome.
Gorka O, Neuwirt E, Groß O. Gorka O, et al. Among authors: gross o. Nat Chem Biol. 2019 Jun;15(6):552-553. doi: 10.1038/s41589-019-0292-8. Nat Chem Biol. 2019. PMID: 31086328 No abstract available.
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade.
Roth S, Cao J, Singh V, Tiedt S, Hundeshagen G, Li T, Boehme JD, Chauhan D, Zhu J, Ricci A, Gorka O, Asare Y, Yang J, Lopez MS, Rehberg M, Bruder D, Zhang S, Groß O, Dichgans M, Hornung V, Liesz A. Roth S, et al. Among authors: gross o. Immunity. 2021 Apr 13;54(4):648-659.e8. doi: 10.1016/j.immuni.2021.02.004. Epub 2021 Mar 4. Immunity. 2021. PMID: 33667383 Free article.
NLRP3 as a sensor of metabolism gone awry.
Neuwirt E, Gorka O, Saller BS, Groß CJ, Madl T, Groß O. Neuwirt E, et al. Among authors: gross cj, gross o. Curr Opin Biotechnol. 2021 Apr;68:300-309. doi: 10.1016/j.copbio.2021.03.009. Epub 2021 Apr 13. Curr Opin Biotechnol. 2021. PMID: 33862489 Review.
Cardiomyocyte-specific miR-100 overexpression preserves heart function under pressure overload in mice and diminishes fatty acid uptake as well as ROS production by direct suppression of Nox4 and CD36.
Smolka C, Schlösser D, Koentges C, Tarkhnishvili A, Gorka O, Pfeifer D, Bemtgen X, Asmussen A, Groß O, Diehl P, Moser M, Bode C, Bugger H, Grundmann S, Pankratz F. Smolka C, et al. Among authors: gross o. FASEB J. 2021 Nov;35(11):e21956. doi: 10.1096/fj.202100829RR. FASEB J. 2021. PMID: 34605573
287 results