Lehner PJ - Search Results

1

A HIF independent oxygen-sensitive pathway for controlling cholesterol synthesis.

Dickson AS, Pauzaite T, Arnaiz E, Ortmann BM, West JA, Volkmar N, Martinelli AW, Li Z, Wit N, Vitkup D, Kaser A, Lehner PJ, Nathan JA. Dickson AS, et al. Among authors: lehner pj. Nat Commun. 2023 Aug 9;14(1):4816. doi: 10.1038/s41467-023-40541-1. Nat Commun. 2023. PMID: 37558666 Free PMC article.

2

The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X.

Nathan JA, Sengupta S, Wood SA, Admon A, Markson G, Sanderson C, Lehner PJ. Nathan JA, et al. Among authors: lehner pj. Traffic. 2008 Jul;9(7):1130-45. doi: 10.1111/j.1600-0854.2008.00747.x. Epub 2008 Apr 11. Traffic. 2008. PMID: 18410486 Free PMC article.

3

The trafficking and regulation of membrane receptors by the RING-CH ubiquitin E3 ligases.

Nathan JA, Lehner PJ. Nathan JA, et al. Among authors: lehner pj. Exp Cell Res. 2009 May 15;315(9):1593-600. doi: 10.1016/j.yexcr.2008.10.026. Epub 2008 Nov 5. Exp Cell Res. 2009. PMID: 19013150 Review.

4

Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression.

Duncan LM, Nathan JA, Lehner PJ. Duncan LM, et al. Among authors: lehner pj. J Immunol. 2010 Jun 15;184(12):6978-85. doi: 10.4049/jimmunol.0904154. Epub 2010 May 12. J Immunol. 2010. PMID: 20483773 Free PMC article.

5

Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins.

Boname JM, Bloor S, Wandel MP, Nathan JA, Antrobus R, Dingwell KS, Thurston TL, Smith DL, Smith JC, Randow F, Lehner PJ. Boname JM, et al. Among authors: lehner pj. J Cell Biol. 2014 Jun 23;205(6):847-62. doi: 10.1083/jcb.201312009. J Cell Biol. 2014. PMID: 24958774 Free PMC article.

6

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

van den Boomen DJ, Timms RT, Grice GL, Stagg HR, Skødt K, Dougan G, Nathan JA, Lehner PJ. van den Boomen DJ, et al. Among authors: lehner pj. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11425-30. doi: 10.1073/pnas.1409099111. Epub 2014 Jul 16. Proc Natl Acad Sci U S A. 2014. PMID: 25030448 Free PMC article.

7

Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions.

Burr SP, Costa AS, Grice GL, Timms RT, Lobb IT, Freisinger P, Dodd RB, Dougan G, Lehner PJ, Frezza C, Nathan JA. Burr SP, et al. Among authors: lehner pj. Cell Metab. 2016 Nov 8;24(5):740-752. doi: 10.1016/j.cmet.2016.09.015. Epub 2016 Oct 27. Cell Metab. 2016. PMID: 27923773 Free PMC article.

8

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins.

Stefanovic-Barrett S, Dickson AS, Burr SP, Williamson JC, Lobb IT, van den Boomen DJ, Lehner PJ, Nathan JA. Stefanovic-Barrett S, et al. Among authors: lehner pj. EMBO Rep. 2018 May;19(5):e45603. doi: 10.15252/embr.201745603. Epub 2018 Mar 8. EMBO Rep. 2018. PMID: 29519897 Free PMC article.

9

The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1.

Menzies SA, Volkmar N, van den Boomen DJ, Timms RT, Dickson AS, Nathan JA, Lehner PJ. Menzies SA, et al. Among authors: lehner pj. Elife. 2018 Dec 13;7:e40009. doi: 10.7554/eLife.40009. Elife. 2018. PMID: 30543180 Free PMC article.

10

Ubiquitin-mediated regulation of sterol homeostasis.

van den Boomen DJH, Volkmar N, Lehner PJ. van den Boomen DJH, et al. Among authors: lehner pj. Curr Opin Cell Biol. 2020 Aug;65:103-111. doi: 10.1016/j.ceb.2020.04.010. Epub 2020 Jun 21. Curr Opin Cell Biol. 2020. PMID: 32580085 Review.

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