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Design, synthesis, anti-inflammatory evaluation, and molecular modelling of new coumarin-based analogs combined curcumin and other heterocycles as potential TNF-α production inhibitors via upregulating Nrf2/HO-1, downregulating AKT/mTOR signalling pathways and downregulating NF-κB in LPS induced macrophages.
Ghany LMAA, Beshay BY, Youssef Moustafa AM, Maghrabi AHA, Ali EHK, Saleem RM, Zaki I, Ryad N. Ghany LMAA, et al. Among authors: ali ehk. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2243551. doi: 10.1080/14756366.2023.2243551. J Enzyme Inhib Med Chem. 2023. PMID: 37558232 Free PMC article.