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L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab.
Marrocco I, Giri S, Simoni-Nieves A, Gupta N, Rudnitsky A, Haga Y, Romaniello D, Sekar A, Zerbib M, Oren R, Lindzen M, Fard D, Tsutsumi Y, Lauriola M, Tamagnone L, Yarden Y. Marrocco I, et al. Among authors: yarden y. Cell Rep Med. 2023 Aug 15;4(8):101142. doi: 10.1016/j.xcrm.2023.101142. Epub 2023 Aug 8. Cell Rep Med. 2023. PMID: 37557179 Free PMC article.
Polyclonal antibody-induced downregulation of HER1/EGFR and HER2 surpasses the effect of combinations of specific registered antibodies.
Bergado-Báez G, Gonzalez Suarez N, García LC, Pérez-Martínez D, Hernández-Fernández DR, Fundora-Barrios T, Rodríguez-Álvarez A, Díaz-Ordaz GD, Lindzen M, Yarden Y, Sánchez-Ramírez B. Bergado-Báez G, et al. Among authors: yarden y. Front Oncol. 2022 Nov 2;12:951267. doi: 10.3389/fonc.2022.951267. eCollection 2022. Front Oncol. 2022. PMID: 36408164 Free PMC article.
Computational optimization of antibody humanness and stability by systematic energy-based ranking.
Tennenhouse A, Khmelnitsky L, Khalaila R, Yeshaya N, Noronha A, Lindzen M, Makowski EK, Zaretsky I, Sirkis YF, Galon-Wolfenson Y, Tessier PM, Abramson J, Yarden Y, Fass D, Fleishman SJ. Tennenhouse A, et al. Among authors: yarden y. Nat Biomed Eng. 2024 Jan;8(1):30-44. doi: 10.1038/s41551-023-01079-1. Epub 2023 Aug 7. Nat Biomed Eng. 2024. PMID: 37550425 Free PMC article.
A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib.
Simoni-Nieves A, Lindzen M, Giri S, Gupta N, Chatterjee R, Selvadurai BR, Van Daele M, Love D, Haga Y, Romaniello D, Salame TM, Zerbib M, Oren R, Tsutsumi Y, Lauriola M, Marrocco I, Yarden Y. Simoni-Nieves A, et al. Among authors: yarden y. Cell Rep Med. 2024 Sep 17;5(9):101703. doi: 10.1016/j.xcrm.2024.101703. Epub 2024 Aug 30. Cell Rep Med. 2024. PMID: 39216477 Free PMC article.
Correction: Modeling invasive breast cancer: growth factors propel progression of HER2-positive premalignant lesions.
Pradeep C-, Zeisel A, Köstler WJ, Lauriola M, Jacob-Hirsch J, Haibe-Kains B, Amariglio N, Ben-Chetrit N, Emde A, Solomonov I, Neufeld G, Piccart M, Sagi I, Sotiriou C, Rechavi G, Domany E, Desmedt C, Yarden Y. Pradeep C-, et al. Among authors: yarden y. Oncogene. 2024 Apr;43(17):1317. doi: 10.1038/s41388-024-02990-w. Oncogene. 2024. PMID: 38418546 No abstract available.
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.
Bojmar L, Zambirinis CP, Hernandez JM, Chakraborty J, Shaashua L, Kim J, Johnson KE, Hanna S, Askan G, Burman J, Ravichandran H, Zheng J, Jolissaint JS, Srouji R, Song Y, Choubey A, Kim HS, Cioffi M, van Beek E, Sigel C, Jessurun J, Velasco Riestra P, Blomstrand H, Jönsson C, Jönsson A, Lauritzen P, Buehring W, Ararso Y, Hernandez D, Vinagolu-Baur JP, Friedman M, Glidden C, Firmenich L, Lieberman G, Mejia DL, Nasar N, Mutvei AP, Paul DM, Bram Y, Costa-Silva B, Basturk O, Boudreau N, Zhang H, Matei IR, Hoshino A, Kelsen D, Sagi I, Scherz A, Scherz-Shouval R, Yarden Y, Oren M, Egeblad M, Lewis JS, Keshari K, Grandgenett PM, Hollingsworth MA, Rajasekhar VK, Healey JH, Björnsson B, Simeone DM, Tuveson DA, Iacobuzio-Donahue CA, Bromberg J, Vincent CT, O'Reilly EM, DeMatteo RP, Balachandran VP, D'Angelica MI, Kingham TP, Allen PJ, Simpson AL, Elemento O, Sandström P, Schwartz RE, Jarnagin WR, Lyden D. Bojmar L, et al. Among authors: yarden y. Nat Med. 2024 Aug;30(8):2170-2180. doi: 10.1038/s41591-024-03075-7. Epub 2024 Jun 28. Nat Med. 2024. PMID: 38942992 Free PMC article.
353 results