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The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.
Nakhe AY, Dadi PK, Kim J, Dickerson MT, Behera S, Dobson JR, Shrestha S, Cartailler JP, Sampson L, Magnuson MA, Jacobson DA. Nakhe AY, et al. Among authors: cartailler jp. bioRxiv [Preprint]. 2024 Feb 27:2023.06.20.545631. doi: 10.1101/2023.06.20.545631. bioRxiv. 2024. Update in: Elife. 2024 May 03;12:RP89967. doi: 10.7554/eLife.89967 PMID: 37546831 Free PMC article. Updated. Preprint.
Research resource: dkCOIN, the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) consortium interconnectivity network: a pilot program to aggregate research resources generated by multiple research consortia.
McKenna NJ, Howard CL, Aufiero M, Easton-Marks J, Steffen DL, Becnel LB, Magnuson MA, McIndoe RA, Cartailler JP. McKenna NJ, et al. Among authors: cartailler jp. Mol Endocrinol. 2012 Oct;26(10):1675-81. doi: 10.1210/me.2012-1077. Epub 2012 Jun 25. Mol Endocrinol. 2012. PMID: 22734043 Free PMC article.
A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development.
Osipovich AB, Dudek KD, Greenfest-Allen E, Cartailler JP, Manduchi E, Potter Case L, Choi E, Chapman AG, Clayton HW, Gu G, Stoeckert CJ Jr, Magnuson MA. Osipovich AB, et al. Among authors: cartailler jp. Development. 2021 Mar 21;148(6):dev196964. doi: 10.1242/dev.196964. Development. 2021. PMID: 33653874 Free PMC article.
44 results