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Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models.
Hopcroft L, Wigmore EM, Williamson SC, Ros S, Eberlein C, Moss JI, Urosevic J, Carnevalli LS, Talbot S, Bradshaw L, Blaker C, Gunda S, Owenson V, Hoffmann S, Sutton D, Jones S, Goodwin RJA, Willis BS, Rooney C, de Bruin EC, Barry ST. Hopcroft L, et al. Among authors: goodwin rja. NPJ Breast Cancer. 2023 Aug 5;9(1):64. doi: 10.1038/s41523-023-00571-w. NPJ Breast Cancer. 2023. PMID: 37543694 Free PMC article.
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo.
Ashton S, Song YH, Nolan J, Cadogan E, Murray J, Odedra R, Foster J, Hall PA, Low S, Taylor P, Ellston R, Polanska UM, Wilson J, Howes C, Smith A, Goodwin RJ, Swales JG, Strittmatter N, Takáts Z, Nilsson A, Andren P, Trueman D, Walker M, Reimer CL, Troiano G, Parsons D, De Witt D, Ashford M, Hrkach J, Zale S, Jewsbury PJ, Barry ST. Ashton S, et al. Sci Transl Med. 2016 Feb 10;8(325):325ra17. doi: 10.1126/scitranslmed.aad2355. Sci Transl Med. 2016. PMID: 26865565 Free article.
High-resolution 3D visualization of nanomedicine distribution in tumors.
Moss JI, Barjat H, Emmas SA, Strittmatter N, Maynard J, Goodwin RJA, Storm G, Lammers T, Puri S, Ashford MB, Barry ST. Moss JI, et al. Among authors: goodwin rja. Theranostics. 2020 Jan 1;10(2):880-897. doi: 10.7150/thno.37178. eCollection 2020. Theranostics. 2020. PMID: 31903157 Free PMC article.
Universal Sample Preparation Unlocking Multimodal Molecular Tissue Imaging.
Dannhorn A, Kazanc E, Ling S, Nikula C, Karali E, Serra MP, Vorng JL, Inglese P, Maglennon G, Hamm G, Swales J, Strittmatter N, Barry ST, Sansom OJ, Poulogiannis G, Bunch J, Goodwin RJ, Takats Z. Dannhorn A, et al. Anal Chem. 2020 Aug 18;92(16):11080-11088. doi: 10.1021/acs.analchem.0c00826. Epub 2020 Jul 27. Anal Chem. 2020. PMID: 32519547
Comparison of 13 C MRI of hyperpolarized [1-13 C]pyruvate and lactate with the corresponding mass spectrometry images in a murine lymphoma model.
Fala M, Somai V, Dannhorn A, Hamm G, Gibson K, Couturier DL, Hesketh R, Wright AJ, Takats Z, Bunch J, Barry ST, Goodwin RJA, Brindle KM. Fala M, et al. Among authors: goodwin rja. Magn Reson Med. 2021 Jun;85(6):3027-3035. doi: 10.1002/mrm.28652. Epub 2021 Jan 9. Magn Reson Med. 2021. PMID: 33421253 Free PMC article.
Method to Investigate the Distribution of Water-Soluble Drug-Delivery Systems in Fresh Frozen Tissues Using Imaging Mass Cytometry.
Strittmatter N, England RM, Race AM, Sutton D, Moss JI, Maglennon G, Ling S, Wong E, Rose J, Purvis I, Macdonald R, Barry ST, Ashford MB, Goodwin RJA. Strittmatter N, et al. Among authors: goodwin rja. Anal Chem. 2021 Mar 2;93(8):3742-3749. doi: 10.1021/acs.analchem.0c03908. Epub 2021 Feb 19. Anal Chem. 2021. PMID: 33606520
GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models.
Brüning-Richardson A, Shaw GC, Tams D, Brend T, Sanganee H, Barry ST, Hamm G, Goodwin RJA, Swales JG, King H, Steele L, Morton R, Widyadari A, Ward TA, Esteves F, Boissinot M, Mavria G, Droop A, Lawler SE, Short SC. Brüning-Richardson A, et al. Among authors: goodwin rja. Cancers (Basel). 2021 Nov 25;13(23):5939. doi: 10.3390/cancers13235939. Cancers (Basel). 2021. PMID: 34885051 Free PMC article.
Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging.
Strittmatter N, Richards FM, Race AM, Ling S, Sutton D, Nilsson A, Wallez Y, Barnes J, Maglennon G, Gopinathan A, Brais R, Wong E, Serra MP, Atkinson J, Smith A, Wilson J, Hamm G, Johnson TI, Dunlop CR, Kaistha BP, Bunch J, Sansom OJ, Takats Z, Andrén PE, Lau A, Barry ST, Goodwin RJA, Jodrell DI. Strittmatter N, et al. Among authors: goodwin rja. Anal Chem. 2022 Jan 25;94(3):1795-1803. doi: 10.1021/acs.analchem.1c04579. Epub 2022 Jan 10. Anal Chem. 2022. PMID: 35005896
95 results