Discovery of Potent and Orally Bioavailable Pyrimidine Amide cGAS Inhibitors via Structure-Guided Hybridization.
Cyr P, Fader LD, Burch JD, Pike KA, Sietsema DV, Boily MO, Ciblat S, Sgarioto N, Skeldon AM, Gaudreault S, Le Gros P, Dumais V, McKay DJJ, Abraham NS, Seliniotakis R, Beveridge RE.
Cyr P, et al. Among authors: mckay djj.
ACS Med Chem Lett. 2024 Nov 25;15(12):2201-2209. doi: 10.1021/acsmedchemlett.4c00471. eCollection 2024 Dec 12.
ACS Med Chem Lett. 2024.
PMID: 39691514