Mao C - Search Results

1

Neutral ceramidase-active site inhibitor chemotypes and binding modes.

Coant N, Bickel JD, Rahaim R, Otsuka Y, Choi YM, Xu R, Simoes M, Cariello C, Mao C, Saied EM, Arenz C, Spicer TP, Bannister TD, Tonge PJ, Airola MV, Scampavia L, Hannun YA, Rizzo RC, Haley JD. Coant N, et al. Among authors: mao c. Bioorg Chem. 2023 Oct;139:106747. doi: 10.1016/j.bioorg.2023.106747. Epub 2023 Jul 27. Bioorg Chem. 2023. PMID: 37531819 Free PMC article.

2

Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs.

Bai A, Szulc ZM, Bielawski J, Pierce JS, Rembiesa B, Terzieva S, Mao C, Xu R, Wu B, Clarke CJ, Newcomb B, Liu X, Norris J, Hannun YA, Bielawska A. Bai A, et al. Among authors: mao c. Bioorg Med Chem. 2014 Dec 15;22(24):6933-44. doi: 10.1016/j.bmc.2014.10.025. Epub 2014 Oct 22. Bioorg Med Chem. 2014. PMID: 25456083 Free PMC article.

3

Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases.

Yi JK, Xu R, Obeid LM, Hannun YA, Airola MV, Mao C. Yi JK, et al. Among authors: mao c. PLoS One. 2022 Sep 1;17(9):e0271540. doi: 10.1371/journal.pone.0271540. eCollection 2022. PLoS One. 2022. PMID: 36048828 Free PMC article.

4

Ceramidases, roles in sphingolipid metabolism and in health and disease.

Coant N, Sakamoto W, Mao C, Hannun YA. Coant N, et al. Among authors: mao c. Adv Biol Regul. 2017 Jan;63:122-131. doi: 10.1016/j.jbior.2016.10.002. Epub 2016 Oct 11. Adv Biol Regul. 2017. PMID: 27771292 Free PMC article. Review.

5

Tumor suppressor p53 links ceramide metabolism to DNA damage response through alkaline ceramidase 2.

Xu R, Garcia-Barros M, Wen S, Li F, Lin CL, Hannun YA, Obeid LM, Mao C. Xu R, et al. Among authors: mao c. Cell Death Differ. 2018 May;25(5):841-856. doi: 10.1038/s41418-017-0018-y. Epub 2017 Dec 11. Cell Death Differ. 2018. PMID: 29229990 Free PMC article.

6

Alkaline ceramidase family: The first two decades.

Xu R, Antwi Boasiako P, Mao C. Xu R, et al. Among authors: mao c. Cell Signal. 2021 Feb;78:109860. doi: 10.1016/j.cellsig.2020.109860. Epub 2020 Dec 1. Cell Signal. 2021. PMID: 33271224 Review.

7

Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase.

Bai A, Mao C, Jenkins RW, Szulc ZM, Bielawska A, Hannun YA. Bai A, et al. Among authors: mao c. PLoS One. 2017 Jun 14;12(6):e0177805. doi: 10.1371/journal.pone.0177805. eCollection 2017. PLoS One. 2017. PMID: 28614356 Free PMC article.

8

Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response.

Xu R, Wang K, Mileva I, Hannun YA, Obeid LM, Mao C. Xu R, et al. Among authors: mao c. Oncotarget. 2016 Apr 5;7(14):18440-57. doi: 10.18632/oncotarget.7825. Oncotarget. 2016. PMID: 26943039 Free PMC article.

9

Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells.

Lin CL, Xu R, Yi JK, Li F, Chen J, Jones EC, Slutsky JB, Huang L, Rigas B, Cao J, Zhong X, Snider AJ, Obeid LM, Hannun YA, Mao C. Lin CL, et al. Among authors: mao c. Stem Cell Reports. 2017 Nov 14;9(5):1488-1500. doi: 10.1016/j.stemcr.2017.09.015. Epub 2017 Oct 19. Stem Cell Reports. 2017. PMID: 29056331 Free PMC article.

10

Transcriptional Regulation of Sphingosine Kinase 1.

Bonica J, Mao C, Obeid LM, Hannun YA. Bonica J, et al. Among authors: mao c. Cells. 2020 Nov 8;9(11):2437. doi: 10.3390/cells9112437. Cells. 2020. PMID: 33171624 Free PMC article. Review.

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