Chiosis G - Search Results

1

Structural and functional complexity of HSP90 in cellular homeostasis and disease.

Chiosis G, Digwal CS, Trepel JB, Neckers L. Chiosis G, et al. Nat Rev Mol Cell Biol. 2023 Nov;24(11):797-815. doi: 10.1038/s41580-023-00640-9. Epub 2023 Jul 31. Nat Rev Mol Cell Biol. 2023. PMID: 37524848 Free PMC article. Review.

2

Vancomycin resistance: occurrence, mechanisms and strategies to combat it.

Boneca IG, Chiosis G. Boneca IG, et al. Among authors: chiosis g. Expert Opin Ther Targets. 2003 Jun;7(3):311-28. doi: 10.1517/14728222.7.3.311. Expert Opin Ther Targets. 2003. PMID: 12783569 Review.

3

Hsp70 molecular chaperones: emerging roles in human disease and identification of small molecule modulators.

Brodsky JL, Chiosis G. Brodsky JL, et al. Among authors: chiosis g. Curr Top Med Chem. 2006;6(11):1215-25. doi: 10.2174/156802606777811997. Curr Top Med Chem. 2006. PMID: 16842158 Review.

4

The yeast Hsp110, Sse1p, exhibits high-affinity peptide binding.

Goeckeler JL, Petruso AP, Aguirre J, Clement CC, Chiosis G, Brodsky JL. Goeckeler JL, et al. Among authors: chiosis g. FEBS Lett. 2008 Jul 9;582(16):2393-6. doi: 10.1016/j.febslet.2008.05.047. Epub 2008 Jun 6. FEBS Lett. 2008. PMID: 18539149 Free PMC article.

5

The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1.

Usmani SZ, Bona RD, Chiosis G, Li Z. Usmani SZ, et al. Among authors: chiosis g. J Hematol Oncol. 2010 Oct 26;3:40. doi: 10.1186/1756-8722-3-40. J Hematol Oncol. 2010. PMID: 20977755 Free PMC article.

6

Identification of novel quaternary domain interactions in the Hsp90 chaperone, GRP94.

Chu F, Maynard JC, Chiosis G, Nicchitta CV, Burlingame AL. Chu F, et al. Among authors: chiosis g. Protein Sci. 2006 Jun;15(6):1260-9. doi: 10.1110/ps.052065106. Protein Sci. 2006. PMID: 16731965 Free PMC article.

7

New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies.

De Martino G, Edler MC, La Regina G, Coluccia A, Barbera MC, Barrow D, Nicholson RI, Chiosis G, Brancale A, Hamel E, Artico M, Silvestri R. De Martino G, et al. Among authors: chiosis g. J Med Chem. 2006 Feb 9;49(3):947-54. doi: 10.1021/jm050809s. J Med Chem. 2006. PMID: 16451061

8

Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins.

Didelot C, Lanneau D, Brunet M, Joly AL, De Thonel A, Chiosis G, Garrido C. Didelot C, et al. Among authors: chiosis g. Curr Med Chem. 2007;14(27):2839-47. doi: 10.2174/092986707782360079. Curr Med Chem. 2007. PMID: 18045130 Review.

9

BCR-ABL point mutants isolated from patients with imatinib mesylate-resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 90.

Gorre ME, Ellwood-Yen K, Chiosis G, Rosen N, Sawyers CL. Gorre ME, et al. Among authors: chiosis g. Blood. 2002 Oct 15;100(8):3041-4. doi: 10.1182/blood-2002-05-1361. Blood. 2002. PMID: 12351420 Free article.

10

Heat shock protein gp96 regulates Toll-like receptor 9 proteolytic processing and conformational stability.

Brooks JC, Sun W, Chiosis G, Leifer CA. Brooks JC, et al. Among authors: chiosis g. Biochem Biophys Res Commun. 2012 May 18;421(4):780-4. doi: 10.1016/j.bbrc.2012.04.083. Epub 2012 Apr 23. Biochem Biophys Res Commun. 2012. PMID: 22554506 Free PMC article.

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