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Wnt signaling inhibits casein kinase 1α activity by modulating its interaction with protein phosphatase 2A.
Shen C, Lu W, Merugu SB, Bharti A, Afify SM, Schnitkey L, Wynn DT, Yang F, Rohwetter TM, Nayak A, Bunnag N, Cywiak C, Tang HY, Harris BT, Albanese C, Ihemelandu C, Cobb MH, Kettenbach A, Lee E, Ahmed Y, Robbins DJ. Shen C, et al. Among authors: lu w. Cell Rep. 2025 Feb 4;44(2):115274. doi: 10.1016/j.celrep.2025.115274. Online ahead of print. Cell Rep. 2025. PMID: 39908140
The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.
He J, Chai X, Zhang Q, Wang Y, Wang Y, Yang X, Wu J, Feng B, Sun J, Rui W, Ze S, Fu Y, Zhao Y, Zhang Y, Zhang Y, Liu M, Liu C, She M, Hu X, Ma X, Yang H, Li D, Zhao S, Li G, Zhang Z, Tian Z, Ma Y, Cao L, Yi B, Li D, Nussinov R, Eng C, Chan TA, Ruppin E, Gutkind JS, Cheng F, Liu M, Lu W. He J, et al. Among authors: lu w. Nat Immunol. 2025 Feb 4. doi: 10.1038/s41590-024-02068-5. Online ahead of print. Nat Immunol. 2025. PMID: 39905201
Sleep-wake variation in body temperature regulates tau secretion and correlates with CSF and plasma tau.
Canet G, Da Gama Monteiro F, Rocaboy E, Diego-Diaz S, Khelaifia B, Godbout K, Lachhab A, Kim J, Valencia DI, Yin A, Wu HT, Howell JC, Blank E, Laliberté F, Fortin N, Boscher E, Fereydouni-Forouzandeh P, Champagne S, Guisle I, Hébert SS, Pernet V, Liu H, Lu W, Debure L, Rapoport DM, Ayappa I, Varga AW, Parekh A, Osorio RS, Lacroix S, Burns MP, Lucey BP, Blessing EM, Planel E. Canet G, et al. Among authors: lu w. J Clin Invest. 2025 Feb 4:e182931. doi: 10.1172/JCI182931. Online ahead of print. J Clin Invest. 2025. PMID: 39903530 Free article.
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