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The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina.
Pruvost M, Patzig J, Yattah C, Selcen I, Hernandez M, Park HJ, Moyon S, Liu S, Morioka MS, Shopland L, Al-Dalahmah O, Bendl J, Fullard JF, Roussos P, Goldman J, He Y, Dupree JL, Casaccia P. Pruvost M, et al. Among authors: park hj. Cell Rep. 2023 Aug 29;42(8):112848. doi: 10.1016/j.celrep.2023.112848. Epub 2023 Jul 28. Cell Rep. 2023. PMID: 37515770 Free PMC article.
A metabolic perspective on CSF-mediated neurodegeneration in multiple sclerosis.
Wentling M, Lopez-Gomez C, Park HJ, Amatruda M, Ntranos A, Aramini J, Petracca M, Rusielewicz T, Chen E, Tolstikov V, Kiebish M, Fossati V, Inglese M, Quinzii CM, Katz Sand I, Casaccia P. Wentling M, et al. Among authors: park hj. Brain. 2019 Sep 1;142(9):2756-2774. doi: 10.1093/brain/awz201. Brain. 2019. PMID: 31305892
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Lim RG, Al-Dalahmah O, Wu J, Gold MP, Reidling JC, Tang G, Adam M, Dansu DK, Park HJ, Casaccia P, Miramontes R, Reyes-Ortiz AM, Lau A, Hickman RA, Khan F, Paryani F, Tang A, Ofori K, Miyoshi E, Michael N, McClure N, Flowers XE, Vonsattel JP, Davidson S, Menon V, Swarup V, Fraenkel E, Goldman JE, Thompson LM. Lim RG, et al. Among authors: park hj. Nat Commun. 2022 Dec 21;13(1):7791. doi: 10.1038/s41467-022-35388-x. Nat Commun. 2022. PMID: 36543778 Free PMC article.
A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion.
Flury A, Aljayousi L, Park HJ, Khakpour M, Mechler J, Aziz S, McGrath JD, Deme P, Sandberg C, González Ibáñez F, Braniff O, Ngo T, Smith S, Velez M, Ramirez DM, Avnon-Klein D, Murray JW, Liu J, Parent M, Mingote S, Haughey NJ, Werneburg S, Tremblay MÈ, Ayata P. Flury A, et al. Among authors: park hj. Neuron. 2024 Dec 19:S0896-6273(24)00875-4. doi: 10.1016/j.neuron.2024.11.018. Online ahead of print. Neuron. 2024. PMID: 39719704
6,380 results