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Page 1
Aluminum Adjuvants-'Back to the Future'.
Laera D, HogenEsch H, O'Hagan DT. Laera D, et al. Among authors: o hagan dt. Pharmaceutics. 2023 Jul 4;15(7):1884. doi: 10.3390/pharmaceutics15071884. Pharmaceutics. 2023. PMID: 37514070 Free PMC article. Review.
A Self-Emulsified Adjuvant System Containing the Immune Potentiator Alpha Tocopherol Induces Higher Neutralizing Antibody Responses than a Squalene-Only Emulsion When Evaluated with a Recombinant Cytomegalovirus (CMV) Pentamer Antigen in Mice.
Lodaya RN, Kanitkar AP, Ashraf A, Bamba D, Amiji MM, O'Hagan DT. Lodaya RN, et al. Among authors: o hagan dt. Pharmaceutics. 2023 Jan 10;15(1):238. doi: 10.3390/pharmaceutics15010238. Pharmaceutics. 2023. PMID: 36678865 Free PMC article.
Systems analysis of human responses to an aluminium hydroxide-adsorbed TLR7 agonist (AS37) adjuvanted vaccine reveals a dose-dependent and specific activation of the interferon-mediated antiviral response.
Siena E, Schiavetti F, Borgogni E, Taccone M, Faenzi E, Brazzoli M, Aprea S, Bardelli M, Volpini G, Buricchi F, Sammicheli C, Tavarini S, Bechtold V, Blohmke CJ, Cardamone D, De Intinis C, Gonzalez-Lopez A, O'Hagan DT, Nuti S, Seidl C, Didierlaurent AM, Bertholet S, D'Oro U, Medini D, Finco O. Siena E, et al. Among authors: o hagan dt. Vaccine. 2023 Jan 16;41(3):724-734. doi: 10.1016/j.vaccine.2022.12.006. Epub 2022 Dec 21. Vaccine. 2023. PMID: 36564274 Free article. Clinical Trial.
MRI/PET multimodal imaging of the innate immune response in skeletal muscle and draining lymph node post vaccination in rats.
Madi S, Xie F, Farhangi K, Hsu CY, Cheng SH, Aweda T, Radaram B, Slania S, Lambert T, Rambo M, Skedzielewski T, Cole A, Sherina V, McKearnan S, Tran H, Alsaid H, Doan M, Stokes AH, O'Hagan DT, Maruggi G, Bertholet S, Temmerman ST, Johnson R, Jucker BM. Madi S, et al. Among authors: o hagan dt. Front Immunol. 2023 Jan 11;13:1081156. doi: 10.3389/fimmu.2022.1081156. eCollection 2022. Front Immunol. 2023. PMID: 36713458 Free PMC article.
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Feng Y, Yuan M, Powers JM, Hu M, Munt JE, Arunachalam PS, Leist SR, Bellusci L, Kim J, Sprouse KR, Adams LE, Sundaramurthy S, Zhu X, Shirreff LM, Mallory ML, Scobey TD, Moreno A, O'Hagan DT, Kleanthous H, Villinger FJ, Veesler D, King NP, Suthar MS, Khurana S, Baric RS, Wilson IA, Pulendran B. Feng Y, et al. Among authors: o hagan dt. Sci Transl Med. 2023 May 10;15(695):eadg7404. doi: 10.1126/scitranslmed.adg7404. Epub 2023 May 10. Sci Transl Med. 2023. PMID: 37163615 Free PMC article.
Extremely potent pan-sarbecovirus neutralizing antibodies generated by immunization of macaques with an AS03-adjuvanted monovalent subunit vaccine against SARS-CoV-2.
Feng Y, Yuan M, Powers JM, Hu M, Munt JE, Arunachalam PS, Leist SR, Bellusci L, Adams LE, Sundaramurthy S, Shirreff LM, Mallory ML, Scooby TD, Moreno A, O'Hagan DT, Kleanthous H, Villinger FJ, Veesler D, King NP, Suthar MS, Khurana S, Baric RS, Wilson IA, Pulendran B. Feng Y, et al. Among authors: o hagan dt. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524784. doi: 10.1101/2023.01.19.524784. bioRxiv. 2023. PMID: 36711543 Free PMC article. Preprint.
179 results