Guengerich FP - Search Results

1

Michael R. Waterman and Cytochrome P450.

Guengerich FP. Guengerich FP. J Inorg Biochem. 2023 Jul 26;247:112328. doi: 10.1016/j.jinorgbio.2023.112328. Online ahead of print. J Inorg Biochem. 2023. PMID: 37506603 No abstract available.

2

Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1).

Lee SG, Kim V, Lee GH, Kim C, Jeong E, Guengerich FP, Kim D. Lee SG, et al. Among authors: guengerich fp. J Inorg Biochem. 2023 Mar;240:112085. doi: 10.1016/j.jinorgbio.2022.112085. Epub 2023 Jan 10. J Inorg Biochem. 2023. PMID: 36640554 Free PMC article.

3

Processive kinetics in the three-step lanosterol 14α-demethylation reaction catalyzed by human cytochrome P450 51A1.

McCarty KD, Sullivan ME, Tateishi Y, Hargrove TY, Lepesheva GI, Guengerich FP. McCarty KD, et al. Among authors: guengerich fp. J Biol Chem. 2023 Jul;299(7):104841. doi: 10.1016/j.jbc.2023.104841. Epub 2023 May 18. J Biol Chem. 2023. PMID: 37209823 Free PMC article.

4

3,4-Desaturation of retinoic acid by cytochrome P450 27C1 prevents P450-mediated catabolism.

Glass SM, Tateishi Y, Guengerich FP, Wang HJ. Glass SM, et al. Among authors: guengerich fp. Arch Biochem Biophys. 2023 Jul 15;743:109669. doi: 10.1016/j.abb.2023.109669. Epub 2023 Jun 24. Arch Biochem Biophys. 2023. PMID: 37356607 Free PMC article.

5

Steroid 17α-hydroxylase/17, 20-lyase (cytochrome P450 17A1).

Guengerich FP, McCarty KD, Tateishi Y, Liu L. Guengerich FP, et al. Methods Enzymol. 2023;689:39-63. doi: 10.1016/bs.mie.2023.04.001. Epub 2023 Apr 25. Methods Enzymol. 2023. PMID: 37802581 Free PMC article.

6

The multistep oxidation of cholesterol to pregnenolone by human cytochrome P450 11A1 is highly processive.

McCarty KD, Liu L, Tateishi Y, Wapshott-Stehli HL, Guengerich FP. McCarty KD, et al. Among authors: guengerich fp. J Biol Chem. 2024 Jan;300(1):105495. doi: 10.1016/j.jbc.2023.105495. Epub 2023 Nov 24. J Biol Chem. 2024. PMID: 38006947 Free PMC article.

7

Ninety-eight semesters of cytochrome P450 enzymes and related topics-What have I taught and learned?

Guengerich FP. Guengerich FP. J Biol Chem. 2024 Feb;300(2):105625. doi: 10.1016/j.jbc.2024.105625. Epub 2024 Jan 5. J Biol Chem. 2024. PMID: 38185246 Free PMC article.

8

Liver fatty acid binding protein FABP1 transfers substrates to cytochrome P450 4A11 for catalysis.

McCarty KD, Guengerich FP. McCarty KD, et al. Among authors: guengerich fp. J Biol Chem. 2025 Jan 8:108168. doi: 10.1016/j.jbc.2025.108168. Online ahead of print. J Biol Chem. 2025. PMID: 39793892 Free article.

9

Oxygen-18 Labeling Reveals a Mixed Fe-O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14α-Demethylation.

McCarty KD, Tateishi Y, Hargrove TY, Lepesheva GI, Guengerich FP. McCarty KD, et al. Among authors: guengerich fp. Angew Chem Int Ed Engl. 2024 Feb 26;63(9):e202317711. doi: 10.1002/anie.202317711. Epub 2024 Jan 24. Angew Chem Int Ed Engl. 2024. PMID: 38206808 Free PMC article.

10

Proteomics, modeling, and fluorescence assays delineate cytochrome b₅ residues involved in binding and stimulation of cytochrome P450 17A1 17,20-lyase.

Tateishi Y, Webb SN, Li B, Liu L, Lindsey Rose K, Leser M, Patel P, Guengerich FP. Tateishi Y, et al. Among authors: guengerich fp. J Biol Chem. 2024 Mar;300(3):105688. doi: 10.1016/j.jbc.2024.105688. Epub 2024 Jan 26. J Biol Chem. 2024. PMID: 38280431 Free PMC article.

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