McLaughlin SH - Search Results

1

Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.

Dendooven T, Zhang Z, Yang J, McLaughlin SH, Schwab J, Scheres SHW, Yatskevich S, Barford D. Dendooven T, et al. Among authors: mclaughlin sh. Sci Adv. 2023 Jul 28;9(30):eadg7480. doi: 10.1126/sciadv.adg7480. Epub 2023 Jul 28. Sci Adv. 2023. PMID: 37506202 Free PMC article.

2

Molecular architecture and mechanism of the anaphase-promoting complex.

Chang LF, Zhang Z, Yang J, McLaughlin SH, Barford D. Chang LF, et al. Among authors: mclaughlin sh. Nature. 2014 Sep 18;513(7518):388-393. doi: 10.1038/nature13543. Epub 2014 Jul 20. Nature. 2014. PMID: 25043029 Free PMC article.

3

Atomic structure of the APC/C and its mechanism of protein ubiquitination.

Chang L, Zhang Z, Yang J, McLaughlin SH, Barford D. Chang L, et al. Among authors: mclaughlin sh. Nature. 2015 Jun 25;522(7557):450-454. doi: 10.1038/nature14471. Epub 2015 Jun 15. Nature. 2015. PMID: 26083744 Free PMC article.

4

Architecture of the CBF3-centromere complex of the budding yeast kinetochore.

Yan K, Zhang Z, Yang J, McLaughlin SH, Barford D. Yan K, et al. Among authors: mclaughlin sh. Nat Struct Mol Biol. 2018 Dec;25(12):1103-1110. doi: 10.1038/s41594-018-0154-1. Epub 2018 Nov 26. Nat Struct Mol Biol. 2018. PMID: 30478265 Free PMC article.

5

Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.

Yan K, Yang J, Zhang Z, McLaughlin SH, Chang L, Fasci D, Ehrenhofer-Murray AE, Heck AJR, Barford D. Yan K, et al. Among authors: mclaughlin sh. Nature. 2019 Oct;574(7777):278-282. doi: 10.1038/s41586-019-1609-1. Epub 2019 Oct 2. Nature. 2019. PMID: 31578520 Free PMC article.

6

Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.

Chang L, Yang J, Jo CH, Boland A, Zhang Z, McLaughlin SH, Abu-Thuraia A, Killoran RC, Smith MJ, Côté JF, Barford D. Chang L, et al. Among authors: mclaughlin sh. Nat Commun. 2020 Jul 10;11(1):3464. doi: 10.1038/s41467-020-17271-9. Nat Commun. 2020. PMID: 32651375 Free PMC article.

7

Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.

Fischer ES, Yu CWH, Bellini D, McLaughlin SH, Orr CM, Wagner A, Freund SMV, Barford D. Fischer ES, et al. Among authors: mclaughlin sh. EMBO Rep. 2021 Jul 5;22(7):e52242. doi: 10.15252/embr.202052242. Epub 2021 May 19. EMBO Rep. 2021. PMID: 34013668 Free PMC article.

8

Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.

Yatskevich S, Muir KW, Bellini D, Zhang Z, Yang J, Tischer T, Predin M, Dendooven T, McLaughlin SH, Barford D. Yatskevich S, et al. Among authors: mclaughlin sh. Science. 2022 May 20;376(6595):844-852. doi: 10.1126/science.abn3810. Epub 2022 Apr 14. Science. 2022. PMID: 35420891 Free PMC article.

9

Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly.

Fischer ES, Yu CWH, Hevler JF, McLaughlin SH, Maslen SL, Heck AJR, Freund SMV, Barford D. Fischer ES, et al. Among authors: mclaughlin sh. Nat Commun. 2022 Oct 26;13(1):6381. doi: 10.1038/s41467-022-34058-2. Nat Commun. 2022. PMID: 36289199 Free PMC article.

10

Disease-specific tau filaments assemble via polymorphic intermediates.

Lövestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW. Lövestam S, et al. Among authors: mclaughlin sh. Nature. 2024 Jan;625(7993):119-125. doi: 10.1038/s41586-023-06788-w. Epub 2023 Nov 29. Nature. 2024. PMID: 38030728 Free PMC article.

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