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Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding.
Riek U, Scholz R, Konarev P, Rufer A, Suter M, Nazabal A, Ringler P, Chami M, Müller SA, Neumann D, Forstner M, Hennig M, Zenobi R, Engel A, Svergun D, Schlattner U, Wallimann T. Riek U, et al. Among authors: rufer a. J Biol Chem. 2008 Jun 27;283(26):18331-43. doi: 10.1074/jbc.M708379200. Epub 2008 Mar 27. J Biol Chem. 2008. PMID: 18372250 Free article.
EFMC: Trends in Medicinal Chemistry and Chemical Biology.
Auberson YP, Arimondo PB, Duca M, Essig S, Grether U, Rufer AC, Sbardella G, Schopfer U, Torrens A, van der Stelt M, Vauzeilles B, Vázquez O, Zhang AX. Auberson YP, et al. Among authors: rufer ac. Chembiochem. 2023 Apr 3;24(7):e202200690. doi: 10.1002/cbic.202200690. Epub 2023 Feb 28. Chembiochem. 2023. PMID: 36704975 Review.
Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.
Aebi J, Atz K, Ametamey SM, Benz J, Blaising J, Butini S, Campiani G, Carreira EM, Collin L, De Lago E, Gazzi T, Gertsch J, Gobbi L, Guba W, Fernández-Ruiz J, Fingerle J, Haider A, He Y, Heitman LH, Honer M, Hunziker D, Kuhn B, Maccarrone M, Märki HP, Martin RE, Mohr P, Mu L, Nazaré M, Nippa DF, Oddi S, O'Hara F, Pacher P, Romero J, Röver S, Rufer AC, Schibli R, Schneider G, Stepan AF, Sykes DA, Ullmer C, Van der Stelt M, Veprintsev DB, Wittwer MB, Grether U. Aebi J, et al. Among authors: rufer ac. Chimia (Aarau). 2024 Aug 21;78(7-8):499-512. doi: 10.2533/chimia.2024.499. Chimia (Aarau). 2024. PMID: 39221845 Free article.
Drug discovery for enzymes.
Rufer AC. Rufer AC. Drug Discov Today. 2021 Apr;26(4):875-886. doi: 10.1016/j.drudis.2021.01.006. Epub 2021 Jan 14. Drug Discov Today. 2021. PMID: 33454380 Free article. Review.
Evaluation of Tetrazine Tracers for Pretargeted Imaging within the Central Nervous System.
Edelmann MR, Bredack C, Belli S, Mohr P, Imhoff MP, Reggiani F, Kusznir EA, Rufer AC, Holt DP, Valentine H, Wong DF, Dannals RF, Honer M, Gobbi LC. Edelmann MR, et al. Among authors: rufer ac. Bioconjug Chem. 2023 Oct 18;34(10):1882-1893. doi: 10.1021/acs.bioconjchem.3c00385. Epub 2023 Sep 14. Bioconjug Chem. 2023. PMID: 37710950
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.
Sarott RC, Westphal MV, Pfaff P, Korn C, Sykes DA, Gazzi T, Brennecke B, Atz K, Weise M, Mostinski Y, Hompluem P, Koers E, Miljuš T, Roth NJ, Asmelash H, Vong MC, Piovesan J, Guba W, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Benito-Cuesta I, Grande T, Ruiz de Martı N Esteban S, Yeliseev A, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Yuan CY, Drobyski WR, Saroz Y, Grimsey N, Honer M, Fingerle J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, McCormick PJ, Ullmer C, Oddi S, Maccarrone M, Veprintsev DB, Nazaré M, Grether U, Carreira EM. Sarott RC, et al. Among authors: rufer ac. J Am Chem Soc. 2020 Oct 7;142(40):16953-16964. doi: 10.1021/jacs.0c05587. Epub 2020 Sep 29. J Am Chem Soc. 2020. PMID: 32902974
68 results