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Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus.
Farr Zuend C, Lamont A, Noel-Romas L, Knodel S, Birse K, Kratzer K, McQueen P, Perner M, Ayele H, Mutch S, Berard AR, Schellenberg JJ, Senturk F, McCorrister S, Westmacott G, Mulhall F, Sandberg B, Yu A, Burnett M, Poliquin V, Burgener AD. Farr Zuend C, et al. Among authors: knodel s. Microbiome. 2023 Jul 25;11(1):159. doi: 10.1186/s40168-023-01594-y. Microbiome. 2023. PMID: 37491398 Free PMC article.
Gut microbiome signatures linked to HIV-1 reservoir size and viremia control.
Borgognone A, Noguera-Julian M, Oriol B, Noël-Romas L, Ruiz-Riol M, Guillén Y, Parera M, Casadellà M, Duran C, Puertas MC, Català-Moll F, De Leon M, Knodel S, Birse K, Manzardo C, Miró JM, Clotet B, Martinez-Picado J, Moltó J, Mothe B, Burgener A, Brander C, Paredes R; BCN02 Study Group. Borgognone A, et al. Among authors: knodel s. Microbiome. 2022 Apr 11;10(1):59. doi: 10.1186/s40168-022-01247-6. Microbiome. 2022. PMID: 35410461 Free PMC article. Clinical Trial.
Non-Lactobacillus-Dominant and Polymicrobial Vaginal Microbiomes Are More Common in Younger South African Women and Predictive of Increased Risk of Human Immunodeficiency Virus Acquisition.
Wang Y, Noël-Romas L, Perner M, Knodel S, Molatlhegi R, Hoger S, Birse K, Zuend CF, McKinnon LR, Burgener AD. Wang Y, et al. Among authors: knodel s. Clin Infect Dis. 2023 Apr 17;76(8):1372-1381. doi: 10.1093/cid/ciac938. Clin Infect Dis. 2023. PMID: 36504254 Free PMC article. Clinical Trial.
Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling.
Berard AR, Brubaker DK, Birse K, Lamont A, Mackelprang RD, Noël-Romas L, Perner M, Hou X, Irungu E, Mugo N, Knodel S, Muwonge TR, Katabira E, Hughes SM, Levy C, Calienes FL, Lauffenburger DA, Baeten JM, Celum C, Hladik F, Lingappa J, Burgener AD. Berard AR, et al. Among authors: knodel s. Cell Rep. 2023 May 30;42(5):112474. doi: 10.1016/j.celrep.2023.112474. Epub 2023 May 6. Cell Rep. 2023. PMID: 37149863 Free PMC article.
Translocating bacteria in SIV infection are not stochastic and preferentially express cytosine methyltransferases.
Flynn JK, Ortiz AM, Vujkovic-Cvijin I, Welles HC, Simpson J, Castello Casta FM, Yee DS, Rahmberg AR, Brooks KL, De Leon M, Knodel S, Birse K, Noel-Romas L, Deewan A, Belkaid Y, Burgener A, Brenchley JM. Flynn JK, et al. Among authors: knodel s. Mucosal Immunol. 2024 Oct;17(5):1089-1101. doi: 10.1016/j.mucimm.2024.07.008. Epub 2024 Jul 31. Mucosal Immunol. 2024. PMID: 39089468 Free PMC article.
A Description of the THRIVE (The Study of Host-Bacterial Relationships and Immune Function in Different Vaginal Environments) Bacterial Vaginosis Observational Study.
Berard AR, Knodel S, Zuend CF, Noël-Romas L, Birse KD, McQueen P, De Leon M, Kratzer K, Taylor OA, Bailey S, Pymar H, Burgener AD, Poliquin V. Berard AR, et al. Among authors: knodel s. J Obstet Gynaecol Can. 2024 Dec;46(12):102667. doi: 10.1016/j.jogc.2024.102667. Epub 2024 Oct 2. J Obstet Gynaecol Can. 2024. PMID: 39362489 Free article.
Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites.
Lawore DC, Jena S, Berard AR, Birse K, Lamont A, Mackelprang RD, Noel-Romas L, Perner M, Hou X, Irungu E, Mugo N, Knodel S, Muwonge TR, Katabira E, Hughes SM, Levy C, Calienes FL, Hladik F, Lingappa JR, Burgener AD, Green LN, Brubaker DK. Lawore DC, et al. Among authors: knodel s. bioRxiv [Preprint]. 2024 Oct 17:2024.10.10.616351. doi: 10.1101/2024.10.10.616351. bioRxiv. 2024. PMID: 39416028 Free PMC article. Preprint.
15 results