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Page 1
Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19.
Robertson SJ, Bedard O, McNally KL, Shaia C, Clancy CS, Lewis M, Broeckel RM, Chiramel AI, Shannon JG, Sturdevant GL, Rosenke R, Anzick SL, Forte E, Preuss C, Baker CN, Harder JM, Brunton C, Munger S, Bruno DP, Lack JB, Leung JM, Shamsaddini A, Gardina P, Sturdevant DE, Sun J, Martens C, Holland SM, Rosenthal NA, Best SM. Robertson SJ, et al. Among authors: chiramel ai. Nat Commun. 2023 Jul 25;14(1):4481. doi: 10.1038/s41467-023-40076-5. Nat Commun. 2023. PMID: 37491352 Free PMC article.
A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection.
Dutta M, Robertson SJ, Okumura A, Scott DP, Chang J, Weiss JM, Sturdevant GL, Feldmann F, Haddock E, Chiramel AI, Ponia SS, Dougherty JD, Katze MG, Rasmussen AL, Best SM. Dutta M, et al. Among authors: chiramel ai. Cell Rep. 2017 Jan 17;18(3):816-829. doi: 10.1016/j.celrep.2016.12.069. Cell Rep. 2017. PMID: 28099857 Free PMC article.
A pigtailed macaque model of Kyasanur Forest disease virus and Alkhurma hemorrhagic disease virus pathogenesis.
Broeckel RM, Feldmann F, McNally KL, Chiramel AI, Sturdevant GL, Leung JM, Hanley PW, Lovaglio J, Rosenke R, Scott DP, Saturday G, Bouamr F, Rasmussen AL, Robertson SJ, Best SM. Broeckel RM, et al. Among authors: chiramel ai. PLoS Pathog. 2021 Dec 2;17(12):e1009678. doi: 10.1371/journal.ppat.1009678. eCollection 2021 Dec. PLoS Pathog. 2021. PMID: 34855915 Free PMC article.
TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation.
Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Méndez-Solís O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM. Chiramel AI, et al. Cell Rep. 2019 Jun 11;27(11):3269-3283.e6. doi: 10.1016/j.celrep.2019.05.040. Cell Rep. 2019. PMID: 31189110 Free PMC article.
Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression.
Lubick KJ, Robertson SJ, McNally KL, Freedman BA, Rasmussen AL, Taylor RT, Walts AD, Tsuruda S, Sakai M, Ishizuka M, Boer EF, Foster EC, Chiramel AI, Addison CB, Green R, Kastner DL, Katze MG, Holland SM, Forlino A, Freeman AF, Boehm M, Yoshii K, Best SM. Lubick KJ, et al. Among authors: chiramel ai. Cell Host Microbe. 2015 Jul 8;18(1):61-74. doi: 10.1016/j.chom.2015.06.007. Cell Host Microbe. 2015. PMID: 26159719 Free PMC article.
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2.
Shi G, Chiramel AI, Li T, Lai KK, Kenney AD, Zani A, Eddy AC, Majdoul S, Zhang L, Dempsey T, Beare PA, Kar S, Yewdell JW, Best SM, Yount JS, Compton AA. Shi G, et al. Among authors: chiramel ai. J Clin Invest. 2022 Dec 15;132(24):e160766. doi: 10.1172/JCI160766. J Clin Invest. 2022. PMID: 36264642 Free PMC article.
24 results