Angulo J - Search Results

1

Imaging Saturation Transfer Difference (STD) NMR: Affinity and Specificity of Protein-Ligand Interactions from a Single NMR Sample.

Monaco S, Angulo J, Wallace M. Monaco S, et al. Among authors: angulo j. J Am Chem Soc. 2023 Aug 2;145(30):16391-16397. doi: 10.1021/jacs.3c02218. Epub 2023 Jul 24. J Am Chem Soc. 2023. PMID: 37487192 Free PMC article.

2

Ligand-receptor binding affinities from saturation transfer difference (STD) NMR spectroscopy: the binding isotherm of STD initial growth rates.

Angulo J, Enríquez-Navas PM, Nieto PM. Angulo J, et al. Chemistry. 2010 Jul 12;16(26):7803-12. doi: 10.1002/chem.200903528. Chemistry. 2010. PMID: 20496354

3

Langerin-heparin interaction: two binding sites for small and large ligands as revealed by a combination of NMR spectroscopy and cross-linking mapping experiments.

Muñoz-García JC, Chabrol E, Vivès RR, Thomas A, de Paz JL, Rojo J, Imberty A, Fieschi F, Nieto PM, Angulo J. Muñoz-García JC, et al. Among authors: angulo j. J Am Chem Soc. 2015 Apr 1;137(12):4100-10. doi: 10.1021/ja511529x. Epub 2015 Mar 23. J Am Chem Soc. 2015. PMID: 25747117

4

Kinetics of intramolecular chemical exchange by initial growth rates of spin saturation transfer difference experiments (SSTD NMR).

Quirós MT, Angulo J, Muñoz MP. Quirós MT, et al. Among authors: angulo j. Chem Commun (Camb). 2015 Jun 25;51(50):10222-5. doi: 10.1039/c5cc02941d. Epub 2015 May 29. Chem Commun (Camb). 2015. PMID: 26022614

5

Unveiling the "Three-Finger Pharmacophore" Required for p53-MDM2 Inhibition by Saturation-Transfer Difference (STD) NMR Initial Growth-Rates Approach.

Angulo J, Goffin SA, Gandhi D, Searcey M, Howell LA. Angulo J, et al. Chemistry. 2016 Apr 18;22(17):5858-62. doi: 10.1002/chem.201600114. Epub 2016 Mar 7. Chemistry. 2016. PMID: 26864212

6

Differential Epitope Mapping by STD NMR Spectroscopy To Reveal the Nature of Protein-Ligand Contacts.

Monaco S, Tailford LE, Juge N, Angulo J. Monaco S, et al. Among authors: angulo j. Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15289-15293. doi: 10.1002/anie.201707682. Epub 2017 Oct 23. Angew Chem Int Ed Engl. 2017. PMID: 28977722 Free PMC article.

7

Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus.

Owen CD, Tailford LE, Monaco S, Šuligoj T, Vaux L, Lallement R, Khedri Z, Yu H, Lecointe K, Walshaw J, Tribolo S, Horrex M, Bell A, Chen X, Taylor GL, Varki A, Angulo J, Juge N. Owen CD, et al. Among authors: angulo j. Nat Commun. 2017 Dec 19;8(1):2196. doi: 10.1038/s41467-017-02109-8. Nat Commun. 2017. PMID: 29259165 Free PMC article.

8

Discovery of Small Molecule WWP2 Ubiquitin Ligase Inhibitors.

Watt JE, Hughes GR, Walpole S, Monaco S, Stephenson GR, Bulman Page PC, Hemmings AM, Angulo J, Chantry A. Watt JE, et al. Among authors: angulo j. Chemistry. 2018 Dec 3;24(67):17677-17680. doi: 10.1002/chem.201804169. Epub 2018 Nov 6. Chemistry. 2018. PMID: 30207403 Free article.

9

Structural basis for arginine glycosylation of host substrates by bacterial effector proteins.

Park JB, Kim YH, Yoo Y, Kim J, Jun SH, Cho JW, El Qaidi S, Walpole S, Monaco S, García-García AA, Wu M, Hays MP, Hurtado-Guerrero R, Angulo J, Hardwidge PR, Shin JS, Cho HS. Park JB, et al. Among authors: angulo j. Nat Commun. 2018 Oct 16;9(1):4283. doi: 10.1038/s41467-018-06680-6. Nat Commun. 2018. PMID: 30327479 Free PMC article.

10

Deriving Ligand Orientation in Weak Protein-Ligand Complexes by DEEP-STD NMR Spectroscopy in the Absence of Protein Chemical-Shift Assignment.

Nepravishta R, Walpole S, Tailford L, Juge N, Angulo J. Nepravishta R, et al. Among authors: angulo j. Chembiochem. 2019 Feb 1;20(3):340-344. doi: 10.1002/cbic.201800568. Epub 2018 Dec 13. Chembiochem. 2019. PMID: 30379391 Free PMC article.

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