Pochet L - Search Results

1

Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy.

Davoine C, Traina A, Evrard J, Lanners S, Fillet M, Pochet L. Davoine C, et al. Among authors: pochet l. Eur J Med Chem. 2023 Nov 5;259:115636. doi: 10.1016/j.ejmech.2023.115636. Epub 2023 Jul 16. Eur J Med Chem. 2023. PMID: 37478556

2

Factor XII/XIIa inhibitors: Their discovery, development, and potential indications.

Davoine C, Bouckaert C, Fillet M, Pochet L. Davoine C, et al. Among authors: pochet l. Eur J Med Chem. 2020 Dec 15;208:112753. doi: 10.1016/j.ejmech.2020.112753. Epub 2020 Aug 20. Eur J Med Chem. 2020. PMID: 32883641 Free article. Review.

3

Fragment Hit Discovery and Binding Site Characterization by Indirect Affinity Capillary Electrophoresis: Application to Factor XIIa.

Davoine C, Pardo A, Pochet L, Fillet M. Davoine C, et al. Among authors: pochet l. Anal Chem. 2021 Nov 9;93(44):14802-14809. doi: 10.1021/acs.analchem.1c03611. Epub 2021 Oct 25. Anal Chem. 2021. PMID: 34694784

4

Capillary electrophoresis as a fragment screening tool to cross-validate hits from chromogenic assay: Application to FXIIa.

Davoine C, Fillet M, Pochet L. Davoine C, et al. Among authors: pochet l. Talanta. 2021 May 1;226:122163. doi: 10.1016/j.talanta.2021.122163. Epub 2021 Feb 2. Talanta. 2021. PMID: 33676706 Free article.

5

Transverse diffusion of laminar flow profiles as a generic capillary electrophoresis method for in-line nanoreactor mixing: Application to the investigation of antithrombotic activity.

Farcaş E, Pochet L, Fillet M. Farcaş E, et al. Among authors: pochet l. Talanta. 2018 Oct 1;188:516-521. doi: 10.1016/j.talanta.2018.06.014. Epub 2018 Jun 7. Talanta. 2018. PMID: 30029407

6

Partial filling affinity capillary electrophoresis as a useful tool for fragment-based drug discovery: A proof of concept on thrombin.

Farcaş E, Bouckaert C, Servais AC, Hanson J, Pochet L, Fillet M. Farcaş E, et al. Among authors: pochet l. Anal Chim Acta. 2017 Sep 1;984:211-222. doi: 10.1016/j.aca.2017.06.035. Epub 2017 Jun 30. Anal Chim Acta. 2017. PMID: 28843566

7

Capillary electrophoretic mobility shift displacement assay for the assessment of weak drug-protein interactions.

Farcaş E, Hanson J, Pochet L, Fillet M. Farcaş E, et al. Among authors: pochet l. Anal Chim Acta. 2018 Nov 30;1034:214-222. doi: 10.1016/j.aca.2018.06.024. Epub 2018 Jun 14. Anal Chim Acta. 2018. PMID: 30193636

8

Determination of inhibitory potency of argatroban toward thrombin by electrophoretically mediated microanalysis.

Pochet L, Servais AC, Farcas E, Bettonville V, Bouckaert C, Fillet M. Pochet L, et al. Talanta. 2013 Nov 15;116:719-25. doi: 10.1016/j.talanta.2013.07.030. Epub 2013 Jul 31. Talanta. 2013. PMID: 24148466

9

Fully automated electrophoretically mediated microanalysis for CYP1A1 activity monitoring optimized by multivariate approach.

Farcaş E, Servais AC, Lamalle C, Chiap P, Pochet L, Fillet M. Farcaş E, et al. Among authors: pochet l. Electrophoresis. 2016 Jan;37(2):248-55. doi: 10.1002/elps.201500214. Epub 2015 Nov 25. Electrophoresis. 2016. PMID: 26462449

10

Capillary electrophoresis in the context of drug discovery.

Farcaş E, Pochet L, Crommen J, Servais AC, Fillet M. Farcaş E, et al. Among authors: pochet l. J Pharm Biomed Anal. 2017 Sep 10;144:195-212. doi: 10.1016/j.jpba.2017.02.022. Epub 2017 Feb 21. J Pharm Biomed Anal. 2017. PMID: 28242155 Review.

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