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442 results

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Fatty acid desaturase 2 determines the lipidomic landscape and steroidogenic function of the adrenal gland.
Witt A, Mateska I, Palladini A, Sinha A, Wölk M, Harauma A, Bechmann N, Pamporaki C, Dahl A, Rothe M, Kopaliani I, Adolf C, Riester A, Wielockx B, Bornstein SR, Kroiss M, Peitzsch M, Moriguchi T, Fedorova M, Grzybek M, Chavakis T, Mirtschink P, Alexaki VI. Witt A, et al. Among authors: rothe m. Sci Adv. 2023 Jul 21;9(29):eadf6710. doi: 10.1126/sciadv.adf6710. Epub 2023 Jul 21. Sci Adv. 2023. PMID: 37478183 Free PMC article.
Sorafenib increases cytochrome P450 lipid metabolites in patient with hepatocellular carcinoma.
Leineweber CG, Rabehl M, Pietzner A, Rohwer N, Rothe M, Pech M, Sangro B, Sharma R, Verslype C, Basu B, Sengel C, Ricke J, Schebb NH, Weylandt KH, Benckert J. Leineweber CG, et al. Among authors: rothe m. Front Pharmacol. 2023 Mar 3;14:1124214. doi: 10.3389/fphar.2023.1124214. eCollection 2023. Front Pharmacol. 2023. PMID: 36937889 Free PMC article.
Studies in Zebrafish and Rat Models Support Dual Blockade of EP2 and EP4 (Prostaglandin E2 Receptors Type 2 and 4) for Renoprotection in Glomerular Hyperfiltration and Albuminuria.
Kourpa A, Schulz A, Mangelsen E, Kaiser-Graf D, Koppers N, Stoll M, Rothe M, Bader M, Purfürst B, Kunz S, Gladytz T, Niendorf T, Bachmann S, Mutig K, Bolbrinker J, Panáková D, Kreutz R. Kourpa A, et al. Among authors: rothe m. Hypertension. 2023 Apr;80(4):771-782. doi: 10.1161/HYPERTENSIONAHA.122.20392. Epub 2023 Jan 30. Hypertension. 2023. PMID: 36715011
Haematopoietic gene therapy of non-conditioned patients with Fanconi anaemia-A: results from open-label phase 1/2 (FANCOLEN-1) and long-term clinical trials.
Río P, Zubicaray J, Navarro S, Gálvez E, Sánchez-Domínguez R, Nicoletti E, Sebastián E, Rothe M, Pujol R, Bogliolo M, John-Neek P, Bastone AL, Schambach A, Wang W, Schmidt M, Larcher L, Segovia JC, Yáñez RM, Alberquilla O, Díez B, Fernández-García M, García-García L, Ramírez M, Galy A, Lefrere F, Cavazzana M, Leblanc T, García de Andoin N, López-Almaraz R, Catalá A, Barquinero J, Rodríguez-Perales S, Rao G, Surrallés J, Soulier J, Díaz-de-Heredia C, Schwartz JD, Sevilla J, Bueren JA; FANCOLEN-1 gene therapy investigators. Río P, et al. Among authors: rothe m. Lancet. 2025 Dec 21;404(10471):2584-2592. doi: 10.1016/S0140-6736(24)01880-4. Epub 2024 Dec 3. Lancet. 2025. PMID: 39642902 Clinical Trial.
Palmitoylcarnitine impairs immunity in decompensated cirrhosis.
Zhang IW, Sánchez-Rodríguez MB, López-Vicario C, Casulleras M, Duran-Güell M, Flores-Costa R, Aguilar F, Rothe M, Segalés P, García-Ruiz C, Fernández-Checa JC, Trebicka J, Arroyo V, Clària J. Zhang IW, et al. Among authors: rothe m. JHEP Rep. 2024 Aug 22;6(11):101187. doi: 10.1016/j.jhepr.2024.101187. eCollection 2024 Nov. JHEP Rep. 2024. PMID: 39524205 Free PMC article.
Palbociclib in Patients With Head and Neck Cancer and Other Tumors With CDKN2A Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study.
Worden FP, Pisick E, Rothe M, Mangat PK, Garrett-Mayer E, Khalil MF, Carrizosa DR, Bauman JR, Leidner RS, Duvivier HL, Fu S, Park MS, Yost KJ, Calfa CJ, Marr AS, Balmanoukian AS, Behl D, Cannon TL, Nabell L, Powell SF, Thota R, Hinshaw DC, Gregory A, Grantham GN, Halabi S, Schilsky RL. Worden FP, et al. Among authors: rothe m. JCO Precis Oncol. 2024 Oct;8:e2400477. doi: 10.1200/PO-24-00477. Epub 2024 Oct 16. JCO Precis Oncol. 2024. PMID: 39413339 Clinical Trial.
Eicosanoid biosynthesizing enzymes in Prototheria.
Kakularam KR, Gündem E, Stehling S, Rothe M, Heydeck D, Kuhn H. Kakularam KR, et al. Among authors: rothe m. Biochim Biophys Acta Mol Cell Biol Lipids. 2025 Jan;1870(1):159569. doi: 10.1016/j.bbalip.2024.159569. Epub 2024 Oct 9. Biochim Biophys Acta Mol Cell Biol Lipids. 2025. PMID: 39389415 Free article.
442 results