Fernandez-Zapico ME - Search Results

1

SUFU promotes GLI activity in a Hedgehog-independent manner in pancreatic cancer.

Paradise BD, Gainullin VG, Almada LL, Sigafoos AN, Sen S, Vera RE, Raja Arul GL, Toruner M, Pease DR, Gonzalez AL, Mentucci FM, Grasso DH, Fernandez-Zapico ME. Paradise BD, et al. Biochem J. 2023 Aug 16;480(15):1199-1216. doi: 10.1042/BCJ20220439. Biochem J. 2023. PMID: 37477952

2

GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis.

Kurita S, Mott JL, Almada LL, Bronk SF, Werneburg NW, Sun SY, Roberts LR, Fernandez-Zapico ME, Gores GJ. Kurita S, et al. Oncogene. 2010 Aug 26;29(34):4848-58. doi: 10.1038/onc.2010.235. Epub 2010 Jun 21. Oncogene. 2010. PMID: 20562908 Free PMC article.

3

Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis.

Ilyas SI, Demars CJ, Comba A, Gainullin VG, Rizvi Z, Almada LL, Wang K, Lomberk G, Fernández-Zapico ME, Buttar NS. Ilyas SI, et al. Cancer Res. 2010 Sep 1;70(17):6787-96. doi: 10.1158/0008-5472.CAN-10-0197. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647328 Free PMC article.

4

A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth.

Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, Almada LL, Han JJ, Mukhopadhyay D, Ordog T, Buttar NS, Urrutia R. Fernandez-Zapico ME, et al. Biochem J. 2011 Apr 15;435(2):529-37. doi: 10.1042/BJ20100773. Biochem J. 2011. PMID: 21171965 Free PMC article.

5

GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment.

Elsawa SF, Almada LL, Ziesmer SC, Novak AJ, Witzig TE, Ansell SM, Fernandez-Zapico ME. Elsawa SF, et al. J Biol Chem. 2011 Jun 17;286(24):21524-34. doi: 10.1074/jbc.M111.234146. Epub 2011 Mar 18. J Biol Chem. 2011. PMID: 21454528 Free PMC article.

6

The alpha subunit of the G protein G13 regulates activity of one or more Gli transcription factors independently of smoothened.

Douglas AE, Heim JA, Shen F, Almada LL, Riobo NA, Fernández-Zapico ME, Manning DR. Douglas AE, et al. J Biol Chem. 2011 Sep 2;286(35):30714-30722. doi: 10.1074/jbc.M111.219279. Epub 2011 Jul 11. J Biol Chem. 2011. PMID: 21757753 Free PMC article.

7

Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity.

Elsawa SF, Novak AJ, Ziesmer SC, Almada LL, Hodge LS, Grote DM, Witzig TE, Fernandez-Zapico ME, Ansell SM. Elsawa SF, et al. Blood. 2011 Nov 17;118(20):5540-9. doi: 10.1182/blood-2011-04-351742. Epub 2011 Sep 14. Blood. 2011. PMID: 21921047 Free PMC article.

8

GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells.

Joost S, Almada LL, Rohnalter V, Holz PS, Vrabel AM, Fernandez-Barrena MG, McWilliams RR, Krause M, Fernandez-Zapico ME, Lauth M. Joost S, et al. Cancer Res. 2012 Jan 1;72(1):88-99. doi: 10.1158/0008-5472.CAN-10-4621. Epub 2011 Nov 15. Cancer Res. 2012. PMID: 22086851 Free PMC article.

9

Novel AKT1-GLI3-VMP1 pathway mediates KRAS oncogene-induced autophagy in cancer cells.

Lo Ré AE, Fernández-Barrena MG, Almada LL, Mills LD, Elsawa SF, Lund G, Ropolo A, Molejon MI, Vaccaro MI, Fernandez-Zapico ME. Lo Ré AE, et al. J Biol Chem. 2012 Jul 20;287(30):25325-34. doi: 10.1074/jbc.M112.370809. Epub 2012 Apr 25. J Biol Chem. 2012. PMID: 22535956 Free PMC article.

10

Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation.

Mills LD, Zhang Y, Marler RJ, Herreros-Villanueva M, Zhang L, Almada LL, Couch F, Wetmore C, Pasca di Magliano M, Fernandez-Zapico ME. Mills LD, et al. J Biol Chem. 2013 Apr 26;288(17):11786-94. doi: 10.1074/jbc.M112.438846. Epub 2013 Mar 12. J Biol Chem. 2013. PMID: 23482563 Free PMC article.

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