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259 results

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Page 1
Evolutionary Pressures Shape Undifferentiated Pleomorphic Sarcoma Development and Radiotherapy Response.
Blomain E, Soudi S, Wang Z, Somani A, Subramanian A, Nouth SCL, Oladipo E, New C, Kenney DE, Nemat-Gorgani N, Kindler T, Avedian RS, Steffner RJ, Mohler DG, Hiniker SM, Chin AL, Kalbasi A, Binkley MS, Fried M, Gaida MM, van de Rijn M, Moding EJ. Blomain E, et al. Among authors: van de rijn m. Cancer Res. 2025 Jan 14. doi: 10.1158/0008-5472.CAN-24-3281. Online ahead of print. Cancer Res. 2025. PMID: 39808162
Safety and efficacy of pembrolizumab, radiation therapy, and surgery versus radiation therapy and surgery for stage III soft tissue sarcoma of the extremity (SU2C-SARC032): an open-label, randomised clinical trial.
Mowery YM, Ballman KV, Hong AM, Schuetze SM, Wagner AJ, Monga V, Heise RS, Attia S, Choy E, Burgess MA, Bae S, Pryor DI, Van Tine BA, Tinoco G, Chmielowski B, Freeman C, Gronchi A, Meyer CF, Dickson MA, Hartner L, Davis LE, Powers BC, Moding EJ, Weinhold KJ, van de Rijn M, Brigman BE, Riedel RF, Kirsch DG. Mowery YM, et al. Among authors: van de rijn m. Lancet. 2024 Nov 23;404(10467):2053-2064. doi: 10.1016/S0140-6736(24)01812-9. Epub 2024 Nov 12. Lancet. 2024. PMID: 39547252 Clinical Trial.
Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes.
Tang YJ, Xu H, Hughes NW, Kim SH, Ruiz P, Shuldiner EG, Lopez SS, Hebert JD, Karmakar S, Andrejka L, Dolcen DN, Boross G, Chu P, Detrick C, Pierce S, Ashkin EL, Greenleaf WJ, Voss AK, Thomas T, van de Rijn M, Petrov DA, Winslow MM. Tang YJ, et al. Among authors: van de rijn m. bioRxiv [Preprint]. 2024 Aug 20:2024.08.19.607671. doi: 10.1101/2024.08.19.607671. bioRxiv. 2024. PMID: 39229041 Free PMC article. Preprint.
Spatially Segregated Macrophage Populations Predict Distinct Outcomes in Colon Cancer.
Matusiak M, Hickey JW, van IJzendoorn DGP, Lu G, Kidziński L, Zhu S, Colburg DRC, Luca B, Phillips DJ, Brubaker SW, Charville GW, Shen J, Loh KM, Okwan-Duodu DK, Nolan GP, Newman AM, West RB, van de Rijn M. Matusiak M, et al. Among authors: van de rijn m. Cancer Discov. 2024 Aug 2;14(8):1418-1439. doi: 10.1158/2159-8290.CD-23-1300. Cancer Discov. 2024. PMID: 38552005 Free PMC article.
Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy.
Subramanian A, Nemat-Gorgani N, Ellis-Caleo TJ, van IJzendoorn DGP, Sears TJ, Somani A, Luca BA, Zhou MY, Bradic M, Torres IA, Oladipo E, New C, Kenney DE, Avedian RS, Steffner RJ, Binkley MS, Mohler DG, Tap WD, D'Angelo SP, van de Rijn M, Ganjoo KN, Bui NQ, Charville GW, Newman AM, Moding EJ. Subramanian A, et al. Among authors: van de rijn m. Nat Cancer. 2024 Apr;5(4):642-658. doi: 10.1038/s43018-024-00743-y. Epub 2024 Mar 1. Nat Cancer. 2024. PMID: 38429415 Free PMC article.
A spatially resolved timeline of the human maternal-fetal interface.
Greenbaum S, Averbukh I, Soon E, Rizzuto G, Baranski A, Greenwald NF, Kagel A, Bosse M, Jaswa EG, Khair Z, Kwok S, Warshawsky S, Piyadasa H, Goldston M, Spence A, Miller G, Schwartz M, Graf W, Van Valen D, Winn VD, Hollmann T, Keren L, van de Rijn M, Angelo M. Greenbaum S, et al. Among authors: van de rijn m. Nature. 2023 Jul;619(7970):595-605. doi: 10.1038/s41586-023-06298-9. Epub 2023 Jul 19. Nature. 2023. PMID: 37468587 Free PMC article.
259 results