Li Q - Search Results

1

Discovery of novel and selective SIK2 inhibitors by the application of AlphaFold structures and generative models.

Zhu W, Liu X, Li Q, Gao F, Liu T, Chen X, Zhang M, Aliper A, Ren F, Ding X, Zhavoronkov A. Zhu W, et al. Among authors: li q. Bioorg Med Chem. 2023 Aug 15;91:117414. doi: 10.1016/j.bmc.2023.117414. Epub 2023 Jul 13. Bioorg Med Chem. 2023. PMID: 37467565

2

Discovery and preclinical profile of YK-2168, a differentiated selective CDK9 inhibitor in clinical development.

Liu Y, Xu Z, Hu L, Xia L, Li Q, Zhou W, Chen Y, Li W, Jiang W, Zhu X, Gao X, Xia Y, Zhu Z, Chen S, Ding CZ. Liu Y, et al. Among authors: li w, li q. Bioorg Med Chem Lett. 2024 Nov 1;112:129941. doi: 10.1016/j.bmcl.2024.129941. Epub 2024 Sep 1. Bioorg Med Chem Lett. 2024. PMID: 39222890

3

A new strategy for the treatment of Parkinson's disease: Discovery and bio-evaluation of the first central-targeting tyrosinase inhibitor.

Qi S, Guo L, Liang J, Wang K, Liao Q, He S, Lyu W, Cheng Z, Wang J, Luo X, Yan X, Lu Z, Wang X, Wang Z, Chen X, Li Q. Qi S, et al. Among authors: li q. Bioorg Chem. 2024 Sep;150:107612. doi: 10.1016/j.bioorg.2024.107612. Epub 2024 Jul 2. Bioorg Chem. 2024. PMID: 38986418

4

Chemoenzymatic synthesis and antileukemic activity of novel C9- and C14-functionalized parthenolide analogs.

Tyagi V, Alwaseem H, O'Dwyer KM, Ponder J, Li QY, Jordan CT, Fasan R. Tyagi V, et al. Bioorg Med Chem. 2016 Sep 1;24(17):3876-3886. doi: 10.1016/j.bmc.2016.06.028. Epub 2016 Jun 16. Bioorg Med Chem. 2016. PMID: 27396927 Free PMC article.

5

NSD3: Advances in cancer therapeutic potential and inhibitors research.

Xiu S, Chi X, Jia Z, Shi C, Zhang X, Li Q, Gao T, Zhang L, Liu Z. Xiu S, et al. Among authors: li q. Eur J Med Chem. 2023 Aug 5;256:115440. doi: 10.1016/j.ejmech.2023.115440. Epub 2023 May 9. Eur J Med Chem. 2023. PMID: 37182335 Review.

6

Discovery of 4-benzylpiperazinequinoline BChE inhibitor that suppresses neuroinflammation for the treatment of Alzheimer's disease.

Chen Y, Zhang W, Li Q, Xie H, Xing S, Lu X, Lyu W, Xiong B, Wang Y, Qu W, Liu W, Chi H, Zhang X, Feng F, Sun H. Chen Y, et al. Among authors: li q. Eur J Med Chem. 2024 Jun 5;272:116463. doi: 10.1016/j.ejmech.2024.116463. Epub 2024 Apr 30. Eur J Med Chem. 2024. PMID: 38704944

7

Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance.

Yan Z, Li Q, Li X, Wang H, Zhao D, Yu H, Guo M, Wang Y, Wang X, Xu H, Mou Y, Hou Z, Guo C. Yan Z, et al. Among authors: li x, li q. J Med Chem. 2024 Aug 8;67(15):12601-12617. doi: 10.1021/acs.jmedchem.4c00593. Epub 2024 Jul 30. J Med Chem. 2024. PMID: 39077891

8

Opportunities and perspectives of small molecular phosphodiesterase inhibitors in neurodegenerative diseases.

Li Q, Liao Q, Qi S, Huang H, He S, Lyu W, Liang J, Qin H, Cheng Z, Yu F, Dong X, Wang Z, Han L, Han Y. Li Q, et al. Eur J Med Chem. 2024 May 5;271:116386. doi: 10.1016/j.ejmech.2024.116386. Epub 2024 Apr 6. Eur J Med Chem. 2024. PMID: 38614063 Review.

9

Targeting glycogen synthase kinase-3β for Alzheimer's disease: Recent advances and future Prospects.

Cheng Z, Han T, Yao J, Wang K, Dong X, Yu F, Huang H, Han M, Liao Q, He S, Lyu W, Li Q. Cheng Z, et al. Among authors: li q. Eur J Med Chem. 2024 Feb 5;265:116065. doi: 10.1016/j.ejmech.2023.116065. Epub 2023 Dec 20. Eur J Med Chem. 2024. PMID: 38160617 Review.

10

Review of triazole scaffolds for treatment and diagnosis of Alzheimer's disease.

Li Q, Qi S, Liang J, Tian Y, He S, Liao Q, Xing S, Han L, Chen X. Li Q, et al. Chem Biol Interact. 2023 Sep 1;382:110623. doi: 10.1016/j.cbi.2023.110623. Epub 2023 Jul 13. Chem Biol Interact. 2023. PMID: 37451665 Review.

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