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Page 1
Conformational restriction shapes the inhibition of a multidrug efflux adaptor protein.
Russell Lewis B, Uddin MR, Moniruzzaman M, Kuo KM, Higgins AJ, Shah LMN, Sobott F, Parks JM, Hammerschmid D, Gumbart JC, Zgurskaya HI, Reading E. Russell Lewis B, et al. Among authors: sobott f. Nat Commun. 2023 Jul 18;14(1):3900. doi: 10.1038/s41467-023-39615-x. Nat Commun. 2023. PMID: 37463890 Free PMC article.
To 200,000 m/z and Beyond: Native Electron Capture Charge Reduction Mass Spectrometry Deconvolves Heterogeneous Signals in Large Biopharmaceutical Analytes.
Le Huray KIP, Wörner TP, Moreira T, Dembek M, Reinhardt-Szyba M, Devine PWA, Bond NJ, Fort KL, Makarov AA, Sobott F. Le Huray KIP, et al. Among authors: sobott f. ACS Cent Sci. 2024 Jul 26;10(8):1548-1561. doi: 10.1021/acscentsci.4c00462. eCollection 2024 Aug 28. ACS Cent Sci. 2024. PMID: 39220705 Free PMC article.
The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins.
McLaughlin SH, Sobott F, Yao ZP, Zhang W, Nielsen PR, Grossmann JG, Laue ED, Robinson CV, Jackson SE. McLaughlin SH, et al. Among authors: sobott f. J Mol Biol. 2006 Feb 24;356(3):746-58. doi: 10.1016/j.jmb.2005.11.085. Epub 2005 Dec 15. J Mol Biol. 2006. PMID: 16403413
Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).
Bulatov E, Martin EM, Chatterjee S, Knebel A, Shimamura S, Konijnenberg A, Johnson C, Zinn N, Grandi P, Sobott F, Ciulli A. Bulatov E, et al. Among authors: sobott f. J Biol Chem. 2015 Feb 13;290(7):4178-91. doi: 10.1074/jbc.M114.616664. Epub 2014 Dec 11. J Biol Chem. 2015. PMID: 25505247 Free PMC article.
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure.
Ponzini E, De Palma A, Cerboni L, Natalello A, Rossi R, Moons R, Konijnenberg A, Narkiewicz J, Legname G, Sobott F, Mauri P, Santambrogio C, Grandori R. Ponzini E, et al. Among authors: sobott f. J Biol Chem. 2019 Apr 5;294(14):5657-5665. doi: 10.1074/jbc.RA118.001907. Epub 2019 Feb 12. J Biol Chem. 2019. PMID: 30755483 Free PMC article.
162 results