Smith DR - Search Results

1

Hepatic and intestinal manganese excretion are both required to regulate brain manganese during elevated manganese exposure.

Hutchens S, Jursa TP, Melkote A, Grant SM, Smith DR, Mukhopadhyay S. Hutchens S, et al. Among authors: smith dr. Am J Physiol Gastrointest Liver Physiol. 2023 Sep 1;325(3):G251-G264. doi: 10.1152/ajpgi.00047.2023. Epub 2023 Jul 18. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 37461848 Free PMC article.

2

SLC30A10 manganese transporter in the brain protects against deficits in motor function and dopaminergic neurotransmission under physiological conditions.

Taylor CA, Grant SM, Jursa T, Melkote A, Fulthorpe R, Aschner M, Smith DR, Gonzales RA, Mukhopadhyay S. Taylor CA, et al. Among authors: smith dr. Metallomics. 2023 Apr 3;15(4):mfad021. doi: 10.1093/mtomcs/mfad021. Metallomics. 2023. PMID: 36990693 Free PMC article.

3

Elevated thyroid manganese reduces thyroid iodine to induce hypothyroidism in mice, but not rats, lacking SLC30A10 transporter.

Hutchens S, Melkote A, Jursa T, Shawlot W, Trasande L, Smith DR, Mukhopadhyay S. Hutchens S, et al. Among authors: smith dr. Metallomics. 2024 Jul 1;16(7):mfae029. doi: 10.1093/mtomcs/mfae029. Metallomics. 2024. PMID: 38866719

4

PHD2 enzyme is an intracellular manganese sensor that initiates the homeostatic response against elevated manganese.

Gurol KC, Jursa T, Cho EJ, Fast W, Dalby KN, Smith DR, Mukhopadhyay S. Gurol KC, et al. Among authors: smith dr. Proc Natl Acad Sci U S A. 2024 Jun 25;121(26):e2402538121. doi: 10.1073/pnas.2402538121. Epub 2024 Jun 21. Proc Natl Acad Sci U S A. 2024. PMID: 38905240 Free PMC article.

5

Methylphenidate alleviates cognitive dysfunction caused by early manganese exposure: Role of catecholaminergic receptors.

Beaudin SA, Howard S, Santiago N, Strupp BJ, Smith DR. Beaudin SA, et al. Among authors: smith dr. Prog Neuropsychopharmacol Biol Psychiatry. 2024 Apr 20;131:110949. doi: 10.1016/j.pnpbp.2024.110949. Epub 2024 Jan 23. Prog Neuropsychopharmacol Biol Psychiatry. 2024. PMID: 38266866 Free article.

6

Maternal choline supplementation lessens the behavioral dysfunction produced by developmental manganese exposure in a rodent model of ADHD.

Howard SL, Beaudin SA, Strupp BJ, Smith DR. Howard SL, et al. Among authors: smith dr. Neurotoxicol Teratol. 2024 Mar-Apr;102:107337. doi: 10.1016/j.ntt.2024.107337. Epub 2024 Feb 27. Neurotoxicol Teratol. 2024. PMID: 38423398

7

Repeated low level domoic acid exposure increases CA1 VGluT1 levels, but not bouton density, VGluT2 or VGAT levels in the hippocampus of adult mice.

Moyer CE, Hiolski EM, Marcinek DJ, Lefebvre KA, Smith DR, Zuo Y. Moyer CE, et al. Among authors: smith dr. Harmful Algae. 2018 Nov;79:74-86. doi: 10.1016/j.hal.2018.08.008. Epub 2018 Sep 5. Harmful Algae. 2018. PMID: 30420019 Free PMC article.

8

Chronic low-level exposure to the common seafood toxin domoic acid causes cognitive deficits in mice.

Lefebvre KA, Kendrick PS, Ladiges W, Hiolski EM, Ferriss BE, Smith DR, Marcinek DJ. Lefebvre KA, et al. Among authors: smith dr. Harmful Algae. 2017 Apr;64:20-29. doi: 10.1016/j.hal.2017.03.003. Epub 2017 Mar 27. Harmful Algae. 2017. PMID: 28427569 Free PMC article.

9

Domoic acid disrupts the activity and connectivity of neuronal networks in organotypic brain slice cultures.

Hiolski EM, Ito S, Beggs JM, Lefebvre KA, Litke AM, Smith DR. Hiolski EM, et al. Among authors: smith dr. Neurotoxicology. 2016 Sep;56:215-224. doi: 10.1016/j.neuro.2016.08.004. Epub 2016 Aug 6. Neurotoxicology. 2016. PMID: 27506300 Free PMC article.

10

Chronic low-level domoic acid exposure alters gene transcription and impairs mitochondrial function in the CNS.

Hiolski EM, Kendrick PS, Frame ER, Myers MS, Bammler TK, Beyer RP, Farin FM, Wilkerson HW, Smith DR, Marcinek DJ, Lefebvre KA. Hiolski EM, et al. Among authors: smith dr. Aquat Toxicol. 2014 Oct;155:151-9. doi: 10.1016/j.aquatox.2014.06.006. Epub 2014 Jun 20. Aquat Toxicol. 2014. PMID: 25033243 Free PMC article.

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