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The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells.
Brina D, Ponzoni A, Troiani M, Calì B, Pasquini E, Attanasio G, Mosole S, Mirenda M, D'Ambrosio M, Colucci M, Guccini I, Revandkar A, Alajati A, Tebaldi T, Donzel D, Lauria F, Parhizgari N, Valdata A, Maddalena M, Calcinotto A, Bolis M, Rinaldi A, Barry S, Rüschoff JH, Sabbadin M, Sumanasuriya S, Crespo M, Sharp A, Yuan W, Grinu M, Boyle A, Miller C, Trotman L, Delaleu N, Fassan M, Moch H, Viero G, de Bono J, Alimonti A. Brina D, et al. Among authors: maddalena m. Nat Cancer. 2023 Aug;4(8):1102-1121. doi: 10.1038/s43018-023-00594-z. Epub 2023 Jul 17. Nat Cancer. 2023. PMID: 37460872 Free PMC article.
Inhibition of MRN activity by a telomere protein motif.
Khayat F, Cannavo E, Alshmery M, Foster WR, Chahwan C, Maddalena M, Smith C, Oliver AW, Watson AT, Carr AM, Cejka P, Bianchi A. Khayat F, et al. Among authors: maddalena m. Nat Commun. 2021 Jun 22;12(1):3856. doi: 10.1038/s41467-021-24047-2. Nat Commun. 2021. PMID: 34158470 Free PMC article.
Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients.
Hassin O, Nataraj NB, Shreberk-Shaked M, Aylon Y, Yaeger R, Fontemaggi G, Mukherjee S, Maddalena M, Avioz A, Iancu O, Mallel G, Gershoni A, Grosheva I, Feldmesser E, Ben-Dor S, Golani O, Hendel A, Blandino G, Kelsen D, Yarden Y, Oren M. Hassin O, et al. Among authors: maddalena m. Nat Commun. 2022 May 19;13(1):2800. doi: 10.1038/s41467-022-30481-7. Nat Commun. 2022. PMID: 35589715 Free PMC article.
TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment.
Maddalena M, Mallel G, Nataraj NB, Shreberk-Shaked M, Hassin O, Mukherjee S, Arandkar S, Rotkopf R, Kapsack A, Lambiase G, Pellegrino B, Ben-Isaac E, Golani O, Addadi Y, Hajaj E, Eilam R, Straussman R, Yarden Y, Lotem M, Oren M. Maddalena M, et al. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2025631118. doi: 10.1073/pnas.2025631118. Proc Natl Acad Sci U S A. 2021. PMID: 34088837 Free PMC article.
Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells.
Dimitrov J, Maddalena M, Terlizzi C, Altobelli GG, Pellegrino S, Mehmood T, De Rosa V, Iommelli F, Del Vecchio S. Dimitrov J, et al. Among authors: maddalena m. Front Immunol. 2024 Oct 4;15:1470620. doi: 10.3389/fimmu.2024.1470620. eCollection 2024. Front Immunol. 2024. PMID: 39430758 Free PMC article.
Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer.
Calì B, Troiani M, Bressan S, Attanasio G, Merler S, Moscarda V, Mosole S, Ricci E, Guo C, Yuan W, Gallagher L, Lundberg A, Bernett I, Figueiredo I, Arzola RA, Abreut EB, D'Ambrosio M, Bancaro N, Brina D, Zumerle S, Pasquini E, Maddalena M, Lai P, Colucci M, Pernigoni N, Rinaldi A, Minardi D, Morlacco A, Moro FD, Sabbadin M, Galuppini F, Fassan M, Rüschoff JH, Moch H, Rescigno P, Francini E, Saieva C, Modesti M, Theurillat JP, Gillessen S, Wilgenbus P, Graf C, Ruf W, de Bono J, Alimonti A. Calì B, et al. Among authors: maddalena m. Cancer Cell. 2024 Oct 14;42(10):1676-1692.e11. doi: 10.1016/j.ccell.2024.08.018. Epub 2024 Sep 19. Cancer Cell. 2024. PMID: 39303726 Free article.
Carcinogenic health outcomes associated with endocrine disrupting chemicals exposure in humans: A wide-scope analysis.
Zeng B, Wu Y, Huang Y, Colucci M, Bancaro N, Maddalena M, Valdata A, Xiong X, Su X, Zhou X, Zhang Z, Jin Y, Huang W, Bai J, Zeng Y, Zou X, Zhan Y, Deng L, Wei Q, Yang L, Alimonti A, Qi F, Qiu S. Zeng B, et al. Among authors: maddalena m. J Hazard Mater. 2024 Sep 5;476:135067. doi: 10.1016/j.jhazmat.2024.135067. Epub 2024 Jul 1. J Hazard Mater. 2024. PMID: 38964039
Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins.
Mukherjee S, Maddalena M, Lü Y, Martinez S, Nataraj NB, Noronha A, Sinha S, Teng K, Cohen-Kaplan V, Ziv T, Arandkar S, Hassin O, Chatterjee R, Pirona AC, Shreberk-Shaked M, Gershoni A, Aylon Y, Elazar Z, Yarden Y, Schramek D, Oren M. Mukherjee S, et al. Among authors: maddalena m. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2119644119. doi: 10.1073/pnas.2119644119. Epub 2022 Apr 19. Proc Natl Acad Sci U S A. 2022. PMID: 35439056 Free PMC article.
25 results