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326 results

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The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils.
Toller-Kawahisa JE, Hiroki CH, Silva CMS, Nascimento DC, Públio GA, Martins TV, Damasceno LEA, Veras FP, Viacava PR, Sukesada FY, Day EA, Zotta A, Ryan TAJ, Moreira da Silva R, Cunha TM, Lopes NP, Cunha FQ, O'Neill LAJ, Alves-Filho JC. Toller-Kawahisa JE, et al. Among authors: lopes np. Nat Commun. 2023 Jul 17;14(1):4280. doi: 10.1038/s41467-023-40021-6. Nat Commun. 2023. PMID: 37460614 Free PMC article.
Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis.
Peres RS, Liew FY, Talbot J, Carregaro V, Oliveira RD, Almeida SL, França RF, Donate PB, Pinto LG, Ferreira FI, Costa DL, Demarque DP, Gouvea DR, Lopes NP, Queiroz RH, Silva JS, Figueiredo F, Alves-Filho JC, Cunha TM, Ferreira SH, Louzada-Junior P, Cunha FQ. Peres RS, et al. Among authors: lopes np. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2509-14. doi: 10.1073/pnas.1424792112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675517 Free PMC article.
Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis.
Peres RS, Santos GB, Cecilio NT, Jabor VA, Niehues M, Torres BG, Buqui G, Silva CH, Costa TD, Lopes NP, Nonato MC, Ramalho FS, Louzada-Júnior P, Cunha TM, Cunha FQ, Emery FS, Alves-Filho JC. Peres RS, et al. Among authors: lopes np. Arthritis Res Ther. 2017 Mar 7;19(1):47. doi: 10.1186/s13075-017-1236-x. Arthritis Res Ther. 2017. PMID: 28270195 Free PMC article.
DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A2A receptor.
Silva RL, Silveira GT, Wanderlei CW, Cecilio NT, Maganin AGM, Franchin M, Marques LMM, Lopes NP, Crippa JA, Guimarães FS, Alves-Filho JCF, Cunha FQ, Cunha TM. Silva RL, et al. Among authors: lopes np. Toxicol Appl Pharmacol. 2019 Apr 1;368:63-71. doi: 10.1016/j.taap.2019.02.011. Epub 2019 Feb 20. Toxicol Appl Pharmacol. 2019. PMID: 30796934
Molecular basis of carrageenan-induced cytokines production in macrophages.
Lopes AH, Silva RL, Fonseca MD, Gomes FI, Maganin AG, Ribeiro LS, Marques LMM, Cunha FQ, Alves-Filho JC, Zamboni DS, Lopes NP, Franklin BS, Gombault A, Ramalho FS, Quesniaux VFJ, Couillin I, Ryffel B, Cunha TM. Lopes AH, et al. Among authors: lopes np. Cell Commun Signal. 2020 Sep 7;18(1):141. doi: 10.1186/s12964-020-00621-x. Cell Commun Signal. 2020. PMID: 32894139 Free PMC article.
326 results