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Screening of predicted synergistic multi-target therapies in glioblastoma identifies new treatment strategies.
Houweling M, Giczewska A, Abdul K, Nieuwenhuis N, Küçükosmanoglu A, Pastuszak K, Buijsman RC, Wesseling P, Wedekind L, Noske D, Supernat A, Bailey D, Watts C, Wurdinger T, Westerman BA. Houweling M, et al. Neurooncol Adv. 2023 Jun 13;5(1):vdad073. doi: 10.1093/noajnl/vdad073. eCollection 2023 Jan-Dec. Neurooncol Adv. 2023. PMID: 37455945 Free PMC article.
WINDOW consortium: A path towards increased therapy efficacy against glioblastoma.
Abdul KU, Houweling M, Svensson F, Narayan RS, Cornelissen FMG, Küçükosmanoglu A, Metzakopian E, Watts C, Bailey D, Wurdinger T, Westerman BA. Abdul KU, et al. Among authors: houweling m. Drug Resist Updat. 2018 Sep;40:17-24. doi: 10.1016/j.drup.2018.10.001. Epub 2018 Oct 30. Drug Resist Updat. 2018. PMID: 30439622 Review.
Radio-sensitizing effect of MEK inhibition in glioblastoma in vitro and in vivo.
Houweling M, Abdul UK, Brahm C, Lagerweij T, Heukelom S, Koken PW, Honeywell R, Wedekind LE, Peters GJ, Verheul H, Sminia P, Noske D, Wurdinger T, Westerman BA. Houweling M, et al. J Cancer Res Clin Oncol. 2023 Jan;149(1):297-305. doi: 10.1007/s00432-022-04483-3. Epub 2022 Dec 1. J Cancer Res Clin Oncol. 2023. PMID: 36451044
A Real-world Toxicity Atlas Shows that Adverse Events of Combination Therapies Commonly Result in Additive Interactions.
Küçükosmanoglu A, Scoarta S, Houweling M, Spinu N, Wijnands T, Geerdink N, Meskers C, Kanev GK, Kiewiet B, Kouwenhoven M, Noske D, Wurdinger T, Pouwer M, Wolff M, Westerman BA. Küçükosmanoglu A, et al. Among authors: houweling m. Clin Cancer Res. 2024 Apr 15;30(8):1685-1695. doi: 10.1158/1078-0432.CCR-23-0914. Clin Cancer Res. 2024. PMID: 38597991 Free PMC article.
Acanthamoeba castellanii trophozoites need oxygen for normal functioning and lipids are their preferred substrate, offering new possibilities for treatment.
Sarink MJ, Mykytyn AZ, Jedidi A, Houweling M, Brouwers JF, Ruijter G, Verbon A, van Hellemond JJ, Tielens AGM. Sarink MJ, et al. Among authors: houweling m. Int J Parasitol. 2025 Jan;55(1):35-44. doi: 10.1016/j.ijpara.2024.10.004. Epub 2024 Oct 26. Int J Parasitol. 2025. PMID: 39490506 Free article.
Early activation of hepatic stellate cells induces rapid initiation of retinyl ester breakdown while maintaining lecithin:retinol acyltransferase (LRAT) activity.
Haaker MW, Goossens V, Hoogland NAN, van Doorne H, Wang Z, Jansen JWA, Kaloyanova DV, van de Lest CHA, Houweling M, Vaandrager AB, Helms JB. Haaker MW, et al. Among authors: houweling m. Biochim Biophys Acta Mol Cell Biol Lipids. 2024 Oct;1869(7):159540. doi: 10.1016/j.bbalip.2024.159540. Epub 2024 Jul 26. Biochim Biophys Acta Mol Cell Biol Lipids. 2024. PMID: 39068984 Free article.
69 results