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Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.
Figg WD Jr, McDonough MA, Chowdhury R, Nakashima Y, Zhang Z, Holt-Martyn JP, Krajnc A, Schofield CJ. Figg WD Jr, et al. Among authors: nakashima y. ChemMedChem. 2021 Jul 6;16(13):2082-2088. doi: 10.1002/cmdc.202100133. Epub 2021 Apr 9. ChemMedChem. 2021. PMID: 33792169 Free PMC article.
A human protein hydroxylase that accepts D-residues.
Choi H, Hardy AP, Leissing TM, Chowdhury R, Nakashima Y, Ge W, Markoulides M, Scotti JS, Gerken PA, Thorbjornsrud H, Kang D, Hong S, Lee J, McDonough MA, Park H, Schofield CJ. Choi H, et al. Among authors: nakashima y. Commun Chem. 2020 May 1;3(1):52. doi: 10.1038/s42004-020-0290-5. Commun Chem. 2020. PMID: 36703414 Free PMC article.
5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5.
Brewitz L, Nakashima Y, Piasecka SK, Salah E, Fletcher SC, Tumber A, Corner TP, Kennedy TJ, Fiorini G, Thalhammer A, Christensen KE, Coleman ML, Schofield CJ. Brewitz L, et al. Among authors: nakashima y. J Med Chem. 2023 Aug 10;66(15):10849-10865. doi: 10.1021/acs.jmedchem.3c01114. Epub 2023 Aug 1. J Med Chem. 2023. PMID: 37527664 Free PMC article.
Human Oxygenase Variants Employing a Single Protein FeII Ligand Are Catalytically Active.
Brasnett A, Pfeffer I, Brewitz L, Chowdhury R, Nakashima Y, Tumber A, McDonough MA, Schofield CJ. Brasnett A, et al. Among authors: nakashima y. Angew Chem Weinheim Bergstr Ger. 2021 Jun 21;133(26):14778-14784. doi: 10.1002/ange.202103711. Epub 2021 May 19. Angew Chem Weinheim Bergstr Ger. 2021. PMID: 38505373 Free PMC article.
2,464 results