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Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design.
Holt GT, Gorman J, Wang S, Lowegard AU, Zhang B, Liu T, Lin BC, Louder MK, Frenkel MS, McKee K, O'Dell S, Rawi R, Shen CH, Doria-Rose NA, Kwong PD, Donald BR. Holt GT, et al. Among authors: lowegard au. Cell Rep. 2023 Jul 25;42(7):112711. doi: 10.1016/j.celrep.2023.112711. Epub 2023 Jul 11. Cell Rep. 2023. PMID: 37436900 Free PMC article.
OSPREY 3.0: Open-source protein redesign for you, with powerful new features.
Hallen MA, Martin JW, Ojewole A, Jou JD, Lowegard AU, Frenkel MS, Gainza P, Nisonoff HM, Mukund A, Wang S, Holt GT, Zhou D, Dowd E, Donald BR. Hallen MA, et al. Among authors: lowegard au. J Comput Chem. 2018 Nov 15;39(30):2494-2507. doi: 10.1002/jcc.25522. Epub 2018 Oct 14. J Comput Chem. 2018. PMID: 30368845 Free PMC article.
Early computational detection of potential high-risk SARS-CoV-2 variants.
Beguir K, Skwark MJ, Fu Y, Pierrot T, Carranza NL, Laterre A, Kadri I, Korched A, Lowegard AU, Lui BG, Sänger B, Liu Y, Poran A, Muik A, Şahin U. Beguir K, et al. Among authors: lowegard au. Comput Biol Med. 2023 Mar;155:106618. doi: 10.1016/j.compbiomed.2023.106618. Epub 2023 Feb 2. Comput Biol Med. 2023. PMID: 36774893 Free PMC article.