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Cell cycle arrest and p53 prevent ON-target megabase-scale rearrangements induced by CRISPR-Cas9.
Cullot G, Boutin J, Fayet S, Prat F, Rosier J, Cappellen D, Lamrissi I, Pennamen P, Bouron J, Amintas S, Thibault C, Moranvillier I, Laharanne E, Merlio JP, Guyonnet-Duperat V, Blouin JM, Richard E, Dabernat S, Moreau-Gaudry F, Bedel A. Cullot G, et al. Among authors: blouin jm. Nat Commun. 2023 Jul 10;14(1):4072. doi: 10.1038/s41467-023-39632-w. Nat Commun. 2023. PMID: 37429857 Free PMC article.
CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells.
Boutin J, Rosier J, Cappellen D, Prat F, Toutain J, Pennamen P, Bouron J, Rooryck C, Merlio JP, Lamrissi-Garcia I, Cullot G, Amintas S, Guyonnet-Duperat V, Ged C, Blouin JM, Richard E, Dabernat S, Moreau-Gaudry F, Bedel A. Boutin J, et al. Among authors: blouin jm. Nat Commun. 2021 Aug 13;12(1):4922. doi: 10.1038/s41467-021-25190-6. Nat Commun. 2021. PMID: 34389729 Free PMC article.
Spleen route accelerates engraftment of human hematopoietic stem cells.
Bedel A, Boutin J, Amintas S, Lamrissi-Garcia I, Rousseau B, Poglio S, Brunet de la Grange P, Moranvillier I, Blouin JM, Richard E, Moreau-Gaudry F, Dabernat S. Bedel A, et al. Among authors: blouin jm. Biochem Biophys Res Commun. 2021 Sep 10;569:23-28. doi: 10.1016/j.bbrc.2021.06.054. Epub 2021 Jul 1. Biochem Biophys Res Commun. 2021. PMID: 34216994
[Clinical and biochemical characterization of childhood urolithiasis].
Giraudon A, Richard E, Godron A, Bouty A, Dobremez E, Barat P, Blouin JM, Llanas B, Harambat J. Giraudon A, et al. Among authors: blouin jm. Arch Pediatr. 2014 Dec;21(12):1322-9. doi: 10.1016/j.arcped.2014.08.027. Epub 2014 Oct 5. Arch Pediatr. 2014. PMID: 25287140 French.
Preventing hyperhomocysteinemia using vitamin B6 supplementation in Givosiran-treated acute intermittent porphyria: Highlights from a case report and brief literature review.
Redonnet-Vernhet I, Mercié P, Lebreton L, Blouin JM, Bronnimann D, Mesli S, Guibet C, Ribeiro E, Gensous N, Duffau P, Gouya L, Richard E. Redonnet-Vernhet I, et al. Among authors: blouin jm. Mol Genet Metab Rep. 2024 Apr 4;39:101076. doi: 10.1016/j.ymgmr.2024.101076. eCollection 2024 Jun. Mol Genet Metab Rep. 2024. PMID: 38601120 Free PMC article.
CRISPR editing to mimic porphyria combined with light: A new preclinical approach for prostate cancer.
Boutin J, Genevois C, Couillaud F, Lamrissi-Garcia I, Guyonnet-Duperat V, Bibeyran A, Lalanne M, Amintas S, Moranvillier I, Richard E, Blouin JM, Dabernat S, Moreau-Gaudry F, Bedel A. Boutin J, et al. Among authors: blouin jm. Mol Ther Oncol. 2024 Feb 8;32(1):200772. doi: 10.1016/j.omton.2024.200772. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596305 Free PMC article.
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