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NOS inhibition reverses TLR2-induced chondrocyte dysfunction and attenuates age-related osteoarthritis.
Shen P, Serve S, Wu P, Liu X, Dai Y, Durán-Hernández N, Nguyen DTM, Fuchs M, Maleitzke T, Reisener MJ, Dzamukova M, Nussbaumer K, Brunner TM, Li Y, Holecska V, Heinz GA, Heinrich F, Durek P, Katsoula G, Gwinner C, Jung T, Zeggini E, Winkler T, Mashreghi MF, Pumberger M, Perka C, Löhning M. Shen P, et al. Among authors: lohning m. Proc Natl Acad Sci U S A. 2023 Jul 18;120(29):e2207993120. doi: 10.1073/pnas.2207993120. Epub 2023 Jul 10. Proc Natl Acad Sci U S A. 2023. PMID: 37428931 Free PMC article.
miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.
Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grün JR, Baumgrass R, Matz M, Löhning M, Scheffold A, Wittmann J, Chang HD, Rajewsky N, Jäck HM, Radbruch A, Mashreghi MF. Haftmann C, et al. Among authors: lohning m. Eur J Immunol. 2015 Apr;45(4):1192-205. doi: 10.1002/eji.201444633. Epub 2015 Jan 22. Eur J Immunol. 2015. PMID: 25486906 Free PMC article.
Enhanced Cell Division Is Required for the Generation of Memory CD4 T Cells to Migrate Into Their Proper Location.
Sarkander J, Hojyo S, Mursell M, Yamasaki Y, Wu TY, Tumes DJ, Miyauchi K, Tran CL, Zhu J, Löhning M, Hutloff A, Mashreghi MF, Kubo M, Radbruch A, Tokoyoda K. Sarkander J, et al. Among authors: lohning m. Front Immunol. 2020 Jan 15;10:3113. doi: 10.3389/fimmu.2019.03113. eCollection 2019. Front Immunol. 2020. PMID: 32010148 Free PMC article.
NK cell receptor NKG2D enforces proinflammatory features and pathogenicity of Th1 and Th17 cells.
Babic M, Dimitropoulos C, Hammer Q, Stehle C, Heinrich F, Sarsenbayeva A, Eisele A, Durek P, Mashreghi MF, Lisnic B, Van Snick J, Löhning M, Fillatreau S, Withers DR, Gagliani N, Huber S, Flavell RA, Polic B, Romagnani C. Babic M, et al. Among authors: lohning m. J Exp Med. 2020 Aug 3;217(8):e20190133. doi: 10.1084/jem.20190133. J Exp Med. 2020. PMID: 32453422 Free PMC article.
Th2 cells lacking T-bet suppress naive and memory T cell responses via IL-10.
Muñoz M, Hegazy AN, Brunner TM, Holecska V, Marek RM, Fröhlich A, Löhning M. Muñoz M, et al. Among authors: lohning m. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2002787118. doi: 10.1073/pnas.2002787118. Proc Natl Acad Sci U S A. 2021. PMID: 33526653 Free PMC article.
Vaccine-elicited CD4 T cells prevent the deletion of antiviral B cells in chronic infection.
Narr K, Ertuna YI, Fallet B, Cornille K, Dimitrova M, Marx AF, Martin K, Abreu Mota T, Künzli M, Schreiner D, Brunner TM, Kreutzfeldt M, Wagner I, Geier F, Bestmann L, Löhning M, Merkler D, King CG, Pinschewer DD. Narr K, et al. Among authors: lohning m. Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2108157118. doi: 10.1073/pnas.2108157118. Proc Natl Acad Sci U S A. 2021. PMID: 34772811 Free PMC article.
85 results