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Depletion of lamins B1 and B2 alters chromatin mobility and induces differential gene expression by a mesoscale-motion dependent mechanism.
Pujadas EM, Wei X, Acosta N, Carter L, Yang J, Almassalha L, Daneshkhah A, Rao SSP, Agrawal V, Seker-Polat F, Aiden EL, Kanemaki MT, Backman V, Adli M. Pujadas EM, et al. Among authors: yang j. bioRxiv [Preprint]. 2023 Jun 26:2023.06.26.546573. doi: 10.1101/2023.06.26.546573. bioRxiv. 2023. Update in: Genome Biol. 2024 Mar 22;25(1):77. doi: 10.1186/s13059-024-03212-y PMID: 37425796 Free PMC article. Updated. Preprint.
Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism.
Pujadas Liwag EM, Wei X, Acosta N, Carter LM, Yang J, Almassalha LM, Jain S, Daneshkhah A, Rao SSP, Seker-Polat F, MacQuarrie KL, Ibarra J, Agrawal V, Aiden EL, Kanemaki MT, Backman V, Adli M. Pujadas Liwag EM, et al. Among authors: yang j. Genome Biol. 2024 Mar 22;25(1):77. doi: 10.1186/s13059-024-03212-y. Genome Biol. 2024. PMID: 38519987 Free PMC article.
Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells.
Wei X, Yang J, Adair SJ, Ozturk H, Kuscu C, Lee KY, Kane WJ, O'Hara PE, Liu D, Demirlenk YM, Habieb AH, Yilmaz E, Dutta A, Bauer TW, Adli M. Wei X, et al. Among authors: yang j. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28068-28079. doi: 10.1073/pnas.2009899117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097661 Free PMC article.
ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer.
Ozturk H, Cingoz H, Tufan T, Yang J, Adair SJ, Tummala KS, Kuscu C, Kinali M, Comertpay G, Nagdas S, Goudreau BJ, Luleyap HU, Bingul Y, Ware TB, Hwang WL, Hsu KL, Kashatus DF, Ting DT, Chandel NS, Bardeesy N, Bauer TW, Adli M. Ozturk H, et al. Among authors: yang j. Dev Cell. 2022 Jun 6;57(11):1331-1346.e9. doi: 10.1016/j.devcel.2022.04.014. Epub 2022 May 3. Dev Cell. 2022. PMID: 35508175 Free article.
Chemotherapy-Induced Distal Enhancers Drive Transcriptional Programs to Maintain the Chemoresistant State in Ovarian Cancer.
Shang S, Yang J, Jazaeri AA, Duval AJ, Tufan T, Lopes Fischer N, Benamar M, Guessous F, Lee I, Campbell RM, Ebert PJ, Abbas T, Landen CN, Difeo A, Scacheri PC, Adli M. Shang S, et al. Among authors: yang j. Cancer Res. 2019 Sep 15;79(18):4599-4611. doi: 10.1158/0008-5472.CAN-19-0215. Epub 2019 Jul 29. Cancer Res. 2019. PMID: 31358529 Free PMC article.
Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy.
Revach OY, Cicerchia AM, Shorer O, Petrova B, Anderson S, Park J, Chen L, Mehta A, Wright SJ, McNamee N, Tal-Mason A, Cattaneo G, Tiwari P, Xie H, Sweere JM, Cheng LC, Sigal N, Enrico E, Miljkovic M, Evans SA, Nguyen N, Whidden ME, Srinivasan R, Spitzer MH, Sun Y, Sharova T, Lawless AR, Michaud WA, Rasmussen MQ, Fang J, Palin CA, Chen F, Wang X, Ferrone CR, Lawrence DP, Sullivan RJ, Liu D, Sachdeva UM, Sen DR, Flaherty KT, Manguso RT, Bod L, Kellis M, Boland GM, Yizhak K, Yang J, Kanarek N, Sade-Feldman M, Hacohen N, Jenkins RW. Revach OY, et al. Among authors: yang j. bioRxiv [Preprint]. 2024 Mar 26:2024.02.12.579184. doi: 10.1101/2024.02.12.579184. bioRxiv. 2024. PMID: 38405985 Free PMC article. Preprint.
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