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Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis.
Hegde S, Marriott AE, Pionnier N, Steven A, Bulman C, Gunderson E, Vogel I, Koschel M, Ehrens A, Lustigman S, Voronin D, Tricoche N, Hoerauf A, Hübner MP, Sakanari J, Aljayyoussi G, Gusovsky F, Dagley J, Hong DW, O'Neill P, Ward SA, Taylor MJ, Turner JD. Hegde S, et al. Among authors: tricoche n. Front Microbiol. 2024 Feb 1;15:1346068. doi: 10.3389/fmicb.2024.1346068. eCollection 2024. Front Microbiol. 2024. PMID: 38362501 Free PMC article.
Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry.
Lin Y, Jung H, Bulman CA, Ng J, Vinck R, O'Beirne C, Zhong S, Moser MS, Tricoche N, Peguero R, Li RW, Urban JF Jr, Le Pape P, Pagniez F, Moretto M, Weil T, Lustigman S, Cariou K, Mitreva M, Sakanari JA, Gasser G. Lin Y, et al. Among authors: tricoche n. J Med Chem. 2023 Dec 14;66(23):15867-15882. doi: 10.1021/acs.jmedchem.3c01333. Epub 2023 Nov 27. J Med Chem. 2023. PMID: 38009931
Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates.
Ryan NM, Hess JA, Robertson EJ, Tricoche N, Turner C, Davis J, Petrovsky N, Ferguson M, Rinaldi WJ, Wong VM, Shimada A, Zhan B, Bottazzi ME, Makepeace BL, Gray SA, Carter D, Lustigman S, Abraham D. Ryan NM, et al. Among authors: tricoche n. Vaccines (Basel). 2023 Jul 6;11(7):1212. doi: 10.3390/vaccines11071212. Vaccines (Basel). 2023. PMID: 37515028 Free PMC article.
Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry.
Lin Y, Jung H, Bulman CA, Ng J, Vinck R, O'Beirne C, Moser MS, Tricoche N, Peguero R, Li RW, Urban JF, Pape PL, Pagniez F, Moretto M, Weil T, Lustigman S, Cariou K, Mitreva M, Sakanari JA, Gasser G. Lin Y, et al. Among authors: tricoche n. bioRxiv [Preprint]. 2023 Jun 30:2023.06.28.546819. doi: 10.1101/2023.06.28.546819. bioRxiv. 2023. Update in: J Med Chem. 2023 Dec 14;66(23):15867-15882. doi: 10.1021/acs.jmedchem.3c01333 PMID: 37425761 Free PMC article. Updated. Preprint.
Pyrvinium Pamoate and Structural Analogs Are Early Macrofilaricide Leads.
Gunderson EL, Bryant C, Bulman CA, Fischer C, Luo M, Vogel I, Lim KC, Jawahar S, Tricoche N, Voronin D, Corbo C, Ayiseh RB, Manfo FPT, Mbah GE, Cho-Ngwa F, Beerntsen B, Renslo AR, Lustigman S, Sakanari JA. Gunderson EL, et al. Among authors: tricoche n. Pharmaceuticals (Basel). 2022 Feb 2;15(2):189. doi: 10.3390/ph15020189. Pharmaceuticals (Basel). 2022. PMID: 35215301 Free PMC article.
Preliminary evaluations of 3-dimensional human skin models for their ability to facilitate in vitro the long-term development of the debilitating obligatory human parasite Onchocerca volvulus.
Malkmus C, Jawahar S, Tricoche N, Lustigman S, Hansmann J. Malkmus C, et al. Among authors: tricoche n. PLoS Negl Trop Dis. 2020 Nov 5;14(11):e0008503. doi: 10.1371/journal.pntd.0008503. eCollection 2020 Nov. PLoS Negl Trop Dis. 2020. PMID: 33151944 Free PMC article.
Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID-19 Patients.
Luchsinger LL, Ransegnola BP, Jin DK, Muecksch F, Weisblum Y, Bao W, George PJ, Rodriguez M, Tricoche N, Schmidt F, Gao C, Jawahar S, Pal M, Schnall E, Zhang H, Strauss D, Yazdanbakhsh K, Hillyer CD, Bieniasz PD, Hatziioannou T. Luchsinger LL, et al. Among authors: tricoche n. J Clin Microbiol. 2020 Nov 18;58(12):e02005-20. doi: 10.1128/JCM.02005-20. Print 2020 Nov 18. J Clin Microbiol. 2020. PMID: 32917729 Free PMC article.
35 results