Tycko R - Search Results

1

Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice.

Gomez-Gutierrez R, Ghosh U, Yau WM, Gamez N, Do K, Kramm C, Shirani H, Vegas-Gomez L, Schulz J, Moreno-Gonzalez I, Gutierrez A, Nilsson KPR, Tycko R, Soto C, Morales R. Gomez-Gutierrez R, et al. Among authors: tycko r. EMBO Rep. 2023 Aug 3;24(8):e57003. doi: 10.15252/embr.202357003. Epub 2023 Jul 10. EMBO Rep. 2023. PMID: 37424505 Free PMC article.

2

Solid-state NMR yields structural constraints on the V3 loop from HIV-1 Gp120 bound to the 447-52D antibody Fv fragment.

Sharpe S, Kessler N, Anglister JA, Yau WM, Tycko R. Sharpe S, et al. Among authors: tycko r. J Am Chem Soc. 2004 Apr 21;126(15):4979-90. doi: 10.1021/ja0392162. J Am Chem Soc. 2004. PMID: 15080704

3

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils.

Petkova AT, Leapman RD, Guo Z, Yau WM, Mattson MP, Tycko R. Petkova AT, et al. Among authors: tycko r. Science. 2005 Jan 14;307(5707):262-5. doi: 10.1126/science.1105850. Science. 2005. PMID: 15653506

4

Expression and purification of a recombinant peptide from the Alzheimer's beta-amyloid protein for solid-state NMR.

Sharpe S, Yau WM, Tycko R. Sharpe S, et al. Among authors: tycko r. Protein Expr Purif. 2005 Jul;42(1):200-10. doi: 10.1016/j.pep.2005.03.005. Epub 2005 Mar 25. Protein Expr Purif. 2005. PMID: 15939307

5

Parallel beta-sheets and polar zippers in amyloid fibrils formed by residues 10-39 of the yeast prion protein Ure2p.

Chan JC, Oyler NA, Yau WM, Tycko R. Chan JC, et al. Among authors: tycko r. Biochemistry. 2005 Aug 9;44(31):10669-80. doi: 10.1021/bi050724t. Biochemistry. 2005. PMID: 16060675 Free PMC article.

6

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils.

Petkova AT, Yau WM, Tycko R. Petkova AT, et al. Among authors: tycko r. Biochemistry. 2006 Jan 17;45(2):498-512. doi: 10.1021/bi051952q. Biochemistry. 2006. PMID: 16401079 Free PMC article.

7

Structure and dynamics of the HIV-1 Vpu transmembrane domain revealed by solid-state NMR with magic-angle spinning.

Sharpe S, Yau WM, Tycko R. Sharpe S, et al. Among authors: tycko r. Biochemistry. 2006 Jan 24;45(3):918-33. doi: 10.1021/bi051766k. Biochemistry. 2006. PMID: 16411768

8

Characterization of beta-sheet structure in Ure2p1-89 yeast prion fibrils by solid-state nuclear magnetic resonance.

Baxa U, Wickner RB, Steven AC, Anderson DE, Marekov LN, Yau WM, Tycko R. Baxa U, et al. Among authors: tycko r. Biochemistry. 2007 Nov 13;46(45):13149-62. doi: 10.1021/bi700826b. Epub 2007 Oct 23. Biochemistry. 2007. PMID: 17953455

9

Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

Luca S, Yau WM, Leapman R, Tycko R. Luca S, et al. Among authors: tycko r. Biochemistry. 2007 Nov 27;46(47):13505-22. doi: 10.1021/bi701427q. Epub 2007 Nov 3. Biochemistry. 2007. PMID: 17979302 Free PMC article.

10

Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils.

Paravastu AK, Leapman RD, Yau WM, Tycko R. Paravastu AK, et al. Among authors: tycko r. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18349-54. doi: 10.1073/pnas.0806270105. Epub 2008 Nov 17. Proc Natl Acad Sci U S A. 2008. PMID: 19015532 Free PMC article.

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