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A family of NADPH/NADP+ biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes.
Scherschel M, Niemeier JO, Jacobs LJHC, Hoffmann MDA, Diederich A, Bell C, Höhne P, Raetz S, Kroll JB, Steinbeck J, Lichtenauer S, Multhoff J, Zimmermann J, Sadhanasatish T, Rothemann RA, Grashoff C, Messens J, Ampofo E, Laschke MW, Riemer J, Roma LP, Schwarzländer M, Morgan B. Scherschel M, et al. Among authors: riemer j. Nat Commun. 2024 Dec 19;15(1):10704. doi: 10.1038/s41467-024-55302-x. Nat Commun. 2024. PMID: 39702652 Free PMC article.
Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast.
Zimmermann J, Lang L, Calabrese G, Laporte H, Amponsah PS, Michalk C, Sukmann T, Oestreicher J, Tursch A, Peker E, Owusu TNE, Weith M, Roma LP, Deponte M, Riemer J, Morgan B. Zimmermann J, et al. Among authors: riemer j. Free Radic Biol Med. 2025 Jan;226:408-420. doi: 10.1016/j.freeradbiomed.2024.11.004. Epub 2024 Nov 6. Free Radic Biol Med. 2025. PMID: 39515595 Free article.
Mitochondrial calcium uniporter complex controls T-cell-mediated immune responses.
Shumanska M, Lodygin D, Gibhardt CS, Ickes C, Stejerean-Todoran I, Krause LCM, Pahl K, Jacobs LJHC, Paluschkiwitz A, Liu S, Boshnakovska A, Voigt N, Legler TJ, Haubrock M, Mitkovski M, Poschmann G, Rehling P, Dennerlein S, Riemer J, Flügel A, Bogeski I. Shumanska M, et al. Among authors: riemer j. EMBO Rep. 2025 Jan;26(2):407-442. doi: 10.1038/s44319-024-00313-4. Epub 2024 Dec 2. EMBO Rep. 2025. PMID: 39623165 Free PMC article.
147 results