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Optogenetic interrogation and control of cell signaling.
Hongdusit A, Liechty ET, Fox JM. Hongdusit A, et al. Among authors: liechty et. Curr Opin Biotechnol. 2020 Dec;66:195-206. doi: 10.1016/j.copbio.2020.07.007. Epub 2020 Oct 11. Curr Opin Biotechnol. 2020. PMID: 33053496 Review.
Analysis of Three Architectures for Controlling PTP1B with Light.
Hongdusit A, Liechty ET, Fox JM. Hongdusit A, et al. Among authors: liechty et. ACS Synth Biol. 2022 Jan 21;11(1):61-68. doi: 10.1021/acssynbio.1c00398. Epub 2021 Dec 13. ACS Synth Biol. 2022. PMID: 34898189 Free PMC article.
Allosteric Inhibition of PTP1B by a Nonpolar Terpenoid.
Friedman AJ, Liechty ET, Kramer L, Sarkar A, Fox JM, Shirts MR. Friedman AJ, et al. Among authors: liechty et. J Phys Chem B. 2022 Oct 27;126(42):8427-8438. doi: 10.1021/acs.jpcb.2c05423. Epub 2022 Oct 12. J Phys Chem B. 2022. PMID: 36223525 Free PMC article.
A biophysical rationale for the selective inhibition of PTP1B over TCPTP by nonpolar terpenoids.
Friedman AJ, Padgette HM, Kramer L, Liechty ET, Donovan GW, Fox JM, Shirts MR. Friedman AJ, et al. Among authors: liechty et. bioRxiv [Preprint]. 2023 Apr 18:2023.04.17.537234. doi: 10.1101/2023.04.17.537234. bioRxiv. 2023. Update in: J Phys Chem B. 2023 Oct 5;127(39):8305-8316. doi: 10.1021/acs.jpcb.3c03791. PMID: 37131728 Free PMC article. Updated. Preprint.