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Page 1
Deep Phenotyping of the Lipidomic Response in COVID and non-COVID Sepsis.
Meng H, Sengupta A, Ricciotti E, Mrčela A, Mathew D, Mazaleuskaya LL, Ghosh S, Brooks TG, Turner AP, Schanoski AS, Lahens NF, Tan AW, Woolfork A, Grant G, Susztak K, Letizia AG, Sealfon SC, Wherry EJ, Laudanski K, Weljie AM, Meyer NB, FitzGerald GA. Meng H, et al. Among authors: wherry ej. bioRxiv [Preprint]. 2023 Jun 2:2023.06.02.543298. doi: 10.1101/2023.06.02.543298. bioRxiv. 2023. Update in: Clin Transl Med. 2023 Nov;13(11):e1440. doi: 10.1002/ctm2.1440 PMID: 37398323 Free PMC article. Updated. Preprint.
Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions.
Mathew D, Giles JR, Baxter AE, Greenplate AR, Wu JE, Alanio C, Oldridge DA, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Hensley SE, Apostolidis S, Huang AC, Vella LA; UPenn COVID Processing Unit; Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. Among authors: wherry ej. bioRxiv [Preprint]. 2020 May 23:2020.05.20.106401. doi: 10.1101/2020.05.20.106401. bioRxiv. 2020. Update in: Science. 2020 Sep 4;369(6508):eabc8511. doi: 10.1126/science.abc8511 PMID: 32511371 Free PMC article. Updated. Preprint.
Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection.
Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum R, Mathew D, Baxter AE, Vella L, Kuthuru O, Apostolidis S, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR. Kuri-Cervantes L, et al. Among authors: wherry ej. bioRxiv [Preprint]. 2020 May 18:2020.05.18.101717. doi: 10.1101/2020.05.18.101717. bioRxiv. 2020. PMID: 32511394 Free PMC article. Preprint.
Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19.
Vella L, Giles JR, Baxter AE, Oldridge DA, Diorio C, Kuri-Cervantes L, Alanio C, Pampena MB, Wu JE, Chen Z, Huang YJ, Anderson EM, Gouma S, McNerney KO, Chase J, Burudpakdee C, Lee JH, Apostolidis SA, Huang AC, Mathew D, Kuthuru O, Goodwin EC, Weirick ME, Bolton MJ, Arevalo CP, Ramos A, Jasen C, Giannini HM, DAndrea K, Meyer NJ, Behrens EM, Bassiri H, Hensley SE, Henrickson SE, Teachey DT, Betts MR, Wherry EJ. Vella L, et al. Among authors: wherry ej. medRxiv [Preprint]. 2020 Oct 6:2020.09.25.20201863. doi: 10.1101/2020.09.25.20201863. medRxiv. 2020. Update in: Sci Immunol. 2021 Mar 2;6(57):eabf7570. doi: 10.1126/sciimmunol.abf7570 PMID: 32995826 Free PMC article. Updated. Preprint.
Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19.
Apostolidis SA, Sarkar A, Giannini HM, Goel RR, Mathew D, Suzuki A, Baxter AE, Greenplate AR, Alanio C, Abdel-Hakeem M, Oldridge DA, Giles J, Wu JE, Chen Z, Huang YJ, Pattekar A, Manne S, Kuthuru O, Dougherty J, Weiderhold B, Weisman AR, Ittner CAG, Gouma S, Dunbar D, Frank I, Huang AC, Vella LA; UPenn COVID Processing Unit; Reilly JP, Hensley SE, Rauova L, Zhao L, Meyer NJ, Poncz M, Abrams CS, Wherry EJ. Apostolidis SA, et al. Among authors: wherry ej. bioRxiv [Preprint]. 2021 May 3:2021.05.01.442279. doi: 10.1101/2021.05.01.442279. bioRxiv. 2021. Update in: Front Immunol. 2022 Mar 03;13:834988. doi: 10.3389/fimmu.2022.834988 PMID: 33972943 Free PMC article. Updated. Preprint.
mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern.
Goel RR, Painter MM, Apostolidis SA, Mathew D, Meng W, Rosenfeld AM, Lundgreen KA, Reynaldi A, Khoury DS, Pattekar A, Gouma S, Kuri-Cervantes L, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Baxter AE, Oldridge DA, Giles JR, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Drapeau EM, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O; UPenn COVID Processing Unit; Frank I, Betts MR, Vella LA, Grifoni A, Weiskopf D, Sette A, Hensley SE, Davenport MP, Bates P, Luning Prak ET, Greenplate AR, Wherry EJ. Goel RR, et al. Among authors: wherry ej. bioRxiv [Preprint]. 2021 Aug 23:2021.08.23.457229. doi: 10.1101/2021.08.23.457229. bioRxiv. 2021. Update in: Science. 2021 Dec 03;374(6572):abm0829. doi: 10.1126/science.abm0829 PMID: 34462751 Free PMC article. Updated. Preprint.
Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine.
Goel RR, Painter MM, Lundgreen KA, Apostolidis SA, Baxter AE, Giles JR, Mathew D, Pattekar A, Reynaldi A, Khoury DS, Gouma S, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Kc W, Oldridge DA, Erickson RI, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O, Drapeau EM, Davenport MP, Hensley SE, Bates P, Greenplate AR, Wherry EJ. Goel RR, et al. Among authors: wherry ej. bioRxiv [Preprint]. 2022 Feb 22:2022.02.20.481163. doi: 10.1101/2022.02.20.481163. bioRxiv. 2022. Update in: Cell. 2022 May 26;185(11):1875-1887.e8. doi: 10.1016/j.cell.2022.04.009 PMID: 35233575 Free PMC article. Updated. Preprint.
Multiethnic Investigation of Risk and Immune Determinants of COVID-19 Outcomes.
Jun T, Mathew D, Sharma N, Nirenberg S, Huang HH, Kovatch P, Wherry EJ, Huang KL. Jun T, et al. Among authors: wherry ej. Front Cell Infect Microbiol. 2022 Jul 22;12:933190. doi: 10.3389/fcimb.2022.933190. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35942057 Free PMC article.
353 results