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The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.
Buerer L, Clark NE, Welch A, Duan C, Taggart AJ, Townley BA, Wang J, Soemedi R, Rong S, Lin CL, Zeng Y, Katolik A, Staley JP, Damha MJ, Mosammaparast N, Fairbrother WG. Buerer L, et al. Among authors: staley jp. Res Sq [Preprint]. 2023 Jun 13:rs.3.rs-2931976. doi: 10.21203/rs.3.rs-2931976/v1. Res Sq. 2023. Update in: Nat Commun. 2024 May 30;15(1):4617. doi: 10.1038/s41467-024-48696-1 PMID: 37398028 Free PMC article. Updated. Preprint.
Elevated levels of intracellular RNA lariats suppress the antiviral response.
Duan C, Buerer L, Bowers C, Taggart AJ, O'Brien MH, Gunasekera S, Lin CL, Wang J, Staley JP, Fredericks AM, Monaghan SF, Welch A, Clark NE, Gao D, Marr N, Zhang SY, Casanova JL, Fairbrother WG. Duan C, et al. Among authors: staley jp. bioRxiv [Preprint]. 2024 Dec 8:2024.12.07.627371. doi: 10.1101/2024.12.07.627371. bioRxiv. 2024. PMID: 39677789 Free PMC article. Preprint.
Global impact of unproductive splicing on human gene expression.
Fair B, Buen Abad Najar CF, Zhao J, Lozano S, Reilly A, Mossian G, Staley JP, Wang J, Li YI. Fair B, et al. Among authors: staley jp. Nat Genet. 2024 Sep;56(9):1851-1861. doi: 10.1038/s41588-024-01872-x. Epub 2024 Sep 2. Nat Genet. 2024. PMID: 39223315 Free PMC article.
The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.
Buerer L, Clark NE, Welch A, Duan C, Taggart AJ, Townley BA, Wang J, Soemedi R, Rong S, Lin CL, Zeng Y, Katolik A, Staley JP, Damha MJ, Mosammaparast N, Fairbrother WG. Buerer L, et al. Among authors: staley jp. Nat Commun. 2024 May 30;15(1):4617. doi: 10.1038/s41467-024-48696-1. Nat Commun. 2024. PMID: 38816363 Free PMC article.
45 results