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Page 1
Ketogenic Diet Reduces Age-Induced Chronic Neuroinflammation in Mice.
Nomura M, Murad NF, Madhavan SS, Mu WC, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC. Nomura M, et al. Among authors: newman jc. Aging Biol. 2024;2:20240038. doi: 10.59368/agingbio.20240038. Epub 2024 Dec 16. Aging Biol. 2024. PMID: 39697898 Free PMC article.
β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain.
Madhavan SS, Roa Diaz S, Peralta S, Nomura M, King CD, Ceyhan KE, Lin A, Bhaumik D, Foulger AC, Shah S, Blade T, Gray W, Chamoli M, Eap B, Panda O, Diaz D, Garcia TY, Stubbs BJ, Ulrich SM, Lithgow GJ, Schilling B, Verdin E, Chaudhuri AR, Newman JC. Madhavan SS, et al. Among authors: newman jc. Cell Chem Biol. 2024 Nov 25:S2451-9456(24)00459-8. doi: 10.1016/j.chembiol.2024.11.001. Online ahead of print. Cell Chem Biol. 2024. PMID: 39626664 Free article.
A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. Alexander M, et al. Among authors: newman jc. Cell Rep. 2024 Nov 26;43(11):114891. doi: 10.1016/j.celrep.2024.114891. Epub 2024 Nov 4. Cell Rep. 2024. PMID: 39500329 Free PMC article.
Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study.
Stubbs BJ, Stephens EB, Senadheera C, Diaz SR, Peralta S, Alexander L, Silverman-Martin W, Kurtzig J, Fernando BA, Yurkovich JT, Garcia TY, Yukawa M, Morris J, Johnson JB, Newman JC. Stubbs BJ, et al. Among authors: newman jc. medRxiv [Preprint]. 2024 Sep 18:2024.09.17.24313811. doi: 10.1101/2024.09.17.24313811. medRxiv. 2024. PMID: 39371165 Free PMC article. Preprint.
Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms.
Stubbs BJ, Alvarez Azañedo G, Peralta S, Diaz SR, Gray W, Alexander L, Silverman-Martin W, Garcia TY, Blonquist TM, Upadhyay V, Turnbaugh PJ, Johnson JB, Newman JC. Stubbs BJ, et al. Among authors: newman jc. PLoS One. 2024 Sep 18;19(9):e0307951. doi: 10.1371/journal.pone.0307951. eCollection 2024. PLoS One. 2024. PMID: 39292659 Free PMC article.
Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study.
Stubbs BJ, Stephens EB, Senadheera C, Peralta S, Roa-Diaz S, Alexander L, Silverman-Martin W, Garcia TY, Yukawa M, Morris J, Blonquist TM, Johnson JB, Newman JC. Stubbs BJ, et al. Among authors: newman jc. J Nutr Health Aging. 2024 Sep;28(9):100329. doi: 10.1016/j.jnha.2024.100329. Epub 2024 Aug 12. J Nutr Health Aging. 2024. PMID: 39137624 Free PMC article. Clinical Trial.
119 results