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DM506 (3-Methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole fumarate), a Novel Derivative of Ibogamine, Inhibits α7 and α9α10 Nicotinic Acetylcholine Receptors by Different Allosteric Mechanisms.
ACS Chem Neurosci. 2023 Jul 19;14(14):2537-2547. doi: 10.1021/acschemneuro.3c00212. Epub 2023 Jun 29.
ACS Chem Neurosci. 2023.
PMID: 37386821
Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.
Hone AJ, Santiago U, Harvey PJ, Tekarli B, Gajewiak J, Craik DJ, Camacho CJ, McIntosh JM.
Hone AJ, et al.
J Med Chem. 2024 Jun 13;67(11):9587-9598. doi: 10.1021/acs.jmedchem.4c00735. Epub 2024 May 30.
J Med Chem. 2024.
PMID: 38814877
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