Romanelli MN - Search Results

1

DM506 (3-Methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole fumarate), a Novel Derivative of Ibogamine, Inhibits α7 and α9α10 Nicotinic Acetylcholine Receptors by Different Allosteric Mechanisms.

Tae HS, Ortells MO, Tekarli BJ, Manetti D, Romanelli MN, McIntosh JM, Adams DJ, Arias HR. Tae HS, et al. Among authors: romanelli mn. ACS Chem Neurosci. 2023 Jul 19;14(14):2537-2547. doi: 10.1021/acschemneuro.3c00212. Epub 2023 Jun 29. ACS Chem Neurosci. 2023. PMID: 37386821

2

Synthesis and pharmacological evaluation of some (pyridyl)cyclopropylmethyl amines and their methiodides as nicotinic receptor ligands.

Guandalini L, Dei S, Manetti D, Romanelli MN, Scapecchi S, Teodori E, Varani K. Guandalini L, et al. Among authors: romanelli mn. Farmaco. 2002 Jun;57(6):487-96. doi: 10.1016/s0014-827x(02)01234-x. Farmaco. 2002. PMID: 12088064

3

AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).

Galeotti N, Ghelardini C, Pittaluga A, Pugliese AM, Bartolini A, Manetti D, Romanelli MN, Gualtieri F. Galeotti N, et al. Among authors: romanelli mn. Naunyn Schmiedebergs Arch Pharmacol. 2003 Dec;368(6):538-45. doi: 10.1007/s00210-003-0812-6. Epub 2003 Nov 5. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 14600801

4

Design of novel nicotinic ligands through 3D database searching.

Guandalini L, Martini E, Dei S, Manetti D, Scapecchi S, Teodori E, Romanelli MN, Varani K, Greco G, Spadola L, Novellino E. Guandalini L, et al. Among authors: romanelli mn. Bioorg Med Chem. 2005 Feb 1;13(3):799-807. doi: 10.1016/j.bmc.2004.10.039. Bioorg Med Chem. 2005. PMID: 15653347

5

Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives.

Dei S, Angeli P, Bellucci C, Buccioni M, Gualtieri F, Marucci G, Manetti D, Matucci R, Romanelli MN, Scapecchi S, Teodori E. Dei S, et al. Among authors: romanelli mn. Biochem Pharmacol. 2005 Jun 1;69(11):1637-45. doi: 10.1016/j.bcp.2005.03.009. Epub 2005 Apr 14. Biochem Pharmacol. 2005. PMID: 15896343

6

Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins.

Manetti D, Di Cesare Mannelli L, Dei S, Galeotti N, Ghelardini C, Romanelli MN, Scapecchi S, Teodori E, Pacini A, Bartolini A, Gualtieri F. Manetti D, et al. Among authors: romanelli mn. J Med Chem. 2005 Oct 6;48(20):6491-503. doi: 10.1021/jm050498l. J Med Chem. 2005. PMID: 16190775

7

Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent.

Martini E, Ghelardini C, Bertucci C, Dei S, Gualtieri F, Guandalini L, Manetti D, Scapecchi S, Teodori E, Romanelli MN. Martini E, et al. Among authors: romanelli mn. Med Chem. 2005 Sep;1(5):473-80. doi: 10.2174/1573406054864142. Med Chem. 2005. PMID: 16787332

8

Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition enhancers.

Romanelli MN, Galeotti N, Ghelardini C, Manetti D, Martini E, Gualtieri F. Romanelli MN, et al. CNS Drug Rev. 2006 Spring;12(1):39-52. doi: 10.1111/j.1527-3458.2006.00039.x. CNS Drug Rev. 2006. PMID: 16834757 Free PMC article. Review.

9

Isomeric N,N-bis(cyclohexanol)amine aryl esters: the discovery of a new class of highly potent P-glycoprotein (Pgp)-dependent multidrug resistance (MDR) inhibitors.

Teodori E, Martelli C, Salerno M, Darghal N, Dei S, Garnier-Suillerot A, Gualtieri F, Manetti D, Scapecchi S, Romanelli MN. Teodori E, et al. Among authors: romanelli mn. J Med Chem. 2007 Feb 22;50(4):599-602. doi: 10.1021/jm0614432. Epub 2007 Jan 26. J Med Chem. 2007. PMID: 17256837

10

Design, synthesis, and preliminary pharmacological evaluation of new quinoline derivatives as nicotinic ligands.

Guandalini L, Norcini M, Varani K, Pistolozzi M, Gotti C, Bazzicalupi C, Martini E, Dei S, Manetti D, Scapecchi S, Teodori E, Bertucci C, Ghelardini C, Romanelli MN. Guandalini L, et al. Among authors: romanelli mn. J Med Chem. 2007 Oct 4;50(20):4993-5002. doi: 10.1021/jm070325r. Epub 2007 Sep 12. J Med Chem. 2007. PMID: 17850058

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