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Page 1
Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes.
Pfefferlé M, Ingoglia G, Schaer CA, Yalamanoglu A, Buzzi R, Dubach IL, Tan G, López-Cano EY, Schulthess N, Hansen K, Humar R, Schaer DJ, Vallelian F. Pfefferlé M, et al. Among authors: vallelian f. J Clin Invest. 2020 Oct 1;130(10):5576-5590. doi: 10.1172/JCI137282. J Clin Invest. 2020. PMID: 32663195 Free PMC article.
Clinical outcomes in patients with systemic lupus erythematosus treated with belimumab in clinical practice settings: a retrospective analysis of results from the OBSErve study in Switzerland.
von Kempis J, Duetsch S, Reuschling N, Villiger R, Villiger PM, Vallelian F, Schaer DJ, Mueller RB. von Kempis J, et al. Among authors: vallelian f. Swiss Med Wkly. 2019 Mar 10;149:w20022. doi: 10.4414/smw.2019.20022. eCollection 2019 Feb 25. Swiss Med Wkly. 2019. PMID: 30852830 Free article.
Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm.
Hugelshofer M, Buzzi RM, Schaer CA, Richter H, Akeret K, Anagnostakou V, Mahmoudi L, Vaccani R, Vallelian F, Deuel JW, Kronen PW, Kulcsar Z, Regli L, Baek JH, Pires IS, Palmer AF, Dennler M, Humar R, Buehler PW, Kircher PR, Keller E, Schaer DJ. Hugelshofer M, et al. Among authors: vallelian f. J Clin Invest. 2019 Dec 2;129(12):5219-5235. doi: 10.1172/JCI130630. J Clin Invest. 2019. PMID: 31454333 Free PMC article.
Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease.
Buehler PW, Swindle D, Pak DI, Ferguson SK, Majka SM, Karoor V, Moldovan R, Sintas C, Black J, Gentinetta T, Buzzi RM, Vallelian F, Wassmer A, Edler M, Bain J, Schu D, Hassell K, Nuss R, Schaer DJ, Irwin DC. Buehler PW, et al. Among authors: vallelian f. Free Radic Biol Med. 2021 Nov 1;175:95-107. doi: 10.1016/j.freeradbiomed.2021.08.238. Epub 2021 Aug 31. Free Radic Biol Med. 2021. PMID: 34478834 Free PMC article.
Erythrophagocytes in hemolytic anemia, wound healing, and cancer.
Humar R, Schaer DJ, Vallelian F. Humar R, et al. Among authors: vallelian f. Trends Mol Med. 2022 Nov;28(11):906-915. doi: 10.1016/j.molmed.2022.08.005. Epub 2022 Sep 10. Trends Mol Med. 2022. PMID: 36096988 Free article. Review.
The reaction of hydrogen peroxide with hemoglobin induces extensive alpha-globin crosslinking and impairs the interaction of hemoglobin with endogenous scavenger pathways.
Vallelian F, Pimenova T, Pereira CP, Abraham B, Mikolajczyk MG, Schoedon G, Zenobi R, Alayash AI, Buehler PW, Schaer DJ. Vallelian F, et al. Free Radic Biol Med. 2008 Oct 15;45(8):1150-8. doi: 10.1016/j.freeradbiomed.2008.07.013. Epub 2008 Jul 27. Free Radic Biol Med. 2008. PMID: 18708138
68 results