Brady GF - Search Results

1

Hepatocyte-specific loss of LAP2α protects against diet-induced hepatic steatosis, steatohepatitis, and fibrosis in male mice.

Upadhyay KK, Choi EK, Foisner R, Omary MB, Brady GF. Upadhyay KK, et al. Among authors: brady gf. Am J Physiol Gastrointest Liver Physiol. 2023 Aug 1;325(2):G184-G195. doi: 10.1152/ajpgi.00214.2022. Epub 2023 Jun 27. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 37366543 Free PMC article.

2

Spectrum of disease associated with partial lipodystrophy: lessons from a trial cohort.

Ajluni N, Meral R, Neidert AH, Brady GF, Buras E, McKenna B, DiPaola F, Chenevert TL, Horowitz JF, Buggs-Saxton C, Rupani AR, Thomas PE, Tayeh MK, Innis JW, Omary MB, Conjeevaram H, Oral EA. Ajluni N, et al. Among authors: brady gf. Clin Endocrinol (Oxf). 2017 May;86(5):698-707. doi: 10.1111/cen.13311. Epub 2017 Mar 27. Clin Endocrinol (Oxf). 2017. PMID: 28199729 Free PMC article.

3

Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity.

Zhang D, Tong X, VanDommelen K, Gupta N, Stamper K, Brady GF, Meng Z, Lin J, Rui L, Omary MB, Yin L. Zhang D, et al. Among authors: brady gf. J Clin Invest. 2017 Jun 30;127(7):2855-2867. doi: 10.1172/JCI89934. Epub 2017 Jun 19. J Clin Invest. 2017. PMID: 28628040 Free PMC article.

4

Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.

Brady GF, Kwan R, Ulintz PJ, Nguyen P, Bassirian S, Basrur V, Nesvizhskii AI, Loomba R, Omary MB. Brady GF, et al. Hepatology. 2018 May;67(5):1710-1725. doi: 10.1002/hep.29522. Epub 2018 Mar 24. Hepatology. 2018. PMID: 28902428 Free PMC article.

5

Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis.

Kwan R, Brady GF, Brzozowski M, Weerasinghe SV, Martin H, Park MJ, Brunt MJ, Menon RK, Tong X, Yin L, Stewart CL, Omary MB. Kwan R, et al. Among authors: brady gf. Cell Mol Gastroenterol Hepatol. 2017 Jul 6;4(3):365-383. doi: 10.1016/j.jcmgh.2017.06.005. eCollection 2017 Nov. Cell Mol Gastroenterol Hepatol. 2017. PMID: 28913408 Free PMC article.

6

Lamins and Lamin-Associated Proteins in Gastrointestinal Health and Disease.

Brady GF, Kwan R, Bragazzi Cunha J, Elenbaas JS, Omary MB. Brady GF, et al. Gastroenterology. 2018 May;154(6):1602-1619.e1. doi: 10.1053/j.gastro.2018.03.026. Epub 2018 Mar 13. Gastroenterology. 2018. PMID: 29549040 Free PMC article. Review.

7

Constitutive release of CPS1 in bile and its role as a protective cytokine during acute liver injury.

Park MJ, D'Alecy LG, Anderson MA, Basrur V, Feng Y, Brady GF, Kim DI, Wu J, Nesvizhskii AI, Lahann J, Lukacs NW, Fontana RJ, Omary MB. Park MJ, et al. Among authors: brady gf. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):9125-9134. doi: 10.1073/pnas.1822173116. Epub 2019 Apr 12. Proc Natl Acad Sci U S A. 2019. PMID: 30979808 Free PMC article.

8

Genotype-phenotype analysis of LMNA-related diseases predicts phenotype-selective alterations in lamin phosphorylation.

Lin EW, Brady GF, Kwan R, Nesvizhskii AI, Omary MB. Lin EW, et al. Among authors: brady gf. FASEB J. 2020 Jul;34(7):9051-9073. doi: 10.1096/fj.202000500R. Epub 2020 May 15. FASEB J. 2020. PMID: 32413188 Free PMC article.

9

A common variant that alters SUN1 degradation associates with hepatic steatosis and metabolic traits in multiple cohorts.

Upadhyay KK, Du X, Chen Y, Buscher B, Chen VL, Oliveri A, Zhao R, Speliotes EK, Brady GF. Upadhyay KK, et al. Among authors: brady gf. J Hepatol. 2023 Nov;79(5):1226-1235. doi: 10.1016/j.jhep.2023.07.036. Epub 2023 Aug 9. J Hepatol. 2023. PMID: 37567366 Free PMC article.

10

LMNA R644C associates with hepatic steatosis in a large cohort and increases cellular lipid droplet accumulation in vitro.

Upadhyay KK, Du X, Chen Y, Speliotes EK, Brady GF. Upadhyay KK, et al. Among authors: brady gf. medRxiv [Preprint]. 2023 Dec 22:2023.12.20.23300290. doi: 10.1101/2023.12.20.23300290. medRxiv. 2023. PMID: 38196593 Free PMC article. Preprint.

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