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Page 1
NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice.
Tran LS, Ying L, D'Costa K, Wray-McCann G, Kerr G, Le L, Allison CC, Ferrand J, Chaudhry H, Emery J, De Paoli A, Colon N, Creed S, Kaparakis-Liaskos M, Como J, Dowling JK, Johanesen PA, Kufer TA, Pedersen JS, Mansell A, Philpott DJ, Elgass KD, Abud HE, Nachbur U, Croker BA, Masters SL, Ferrero RL. Tran LS, et al. Among authors: masters sl. Nat Commun. 2023 Jun 26;14(1):3804. doi: 10.1038/s41467-023-39487-1. Nat Commun. 2023. PMID: 37365163 Free PMC article.
NLRP1a expression in Srebp-1a-deficient mice.
Gerlic M, Croker BA, Cengia LH, Moayeri M, Kile BT, Masters SL. Gerlic M, et al. Among authors: masters sl. Cell Metab. 2014 Mar 4;19(3):345-6. doi: 10.1016/j.cmet.2014.02.002. Cell Metab. 2014. PMID: 24606891 Free article. No abstract available.
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T, Vince JE, Lawlor KE, Ninnis RL, Anderton H, Hall C, Spall SK, Phesse TJ, Abud HE, Cengia LH, Corbin J, Mifsud S, Di Rago L, Metcalf D, Ernst M, Dewson G, Roberts AW, Alexander WS, Murphy JM, Ekert PG, Masters SL, Vaux DL, Croker BA, Gerlic M, Silke J. Rickard JA, et al. Among authors: masters sl. Cell. 2014 May 22;157(5):1175-88. doi: 10.1016/j.cell.2014.04.019. Epub 2014 May 8. Cell. 2014. PMID: 24813849 Free article.
Fas regulates neutrophil lifespan during viral and bacterial infection.
O'Donnell JA, Kennedy CL, Pellegrini M, Nowell CJ, Zhang JG, O'Reilly LA, Cengia L, Dias S, Masters SL, Hartland EL, Roberts AW, Gerlic M, Croker BA. O'Donnell JA, et al. Among authors: masters sl. J Leukoc Biol. 2015 Feb;97(2):321-6. doi: 10.1189/jlb.3AB1113-594RR. Epub 2014 Dec 3. J Leukoc Biol. 2015. PMID: 25473101
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, Vetter I, Dungan LS, Monks BG, Stutz A, Croker DE, Butler MS, Haneklaus M, Sutton CE, Núñez G, Latz E, Kastner DL, Mills KH, Masters SL, Schroder K, Cooper MA, O'Neill LA. Coll RC, et al. Among authors: masters sl. Nat Med. 2015 Mar;21(3):248-55. doi: 10.1038/nm.3806. Epub 2015 Feb 16. Nat Med. 2015. PMID: 25686105 Free PMC article.
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
Lawlor KE, Khan N, Mildenhall A, Gerlic M, Croker BA, D'Cruz AA, Hall C, Kaur Spall S, Anderton H, Masters SL, Rashidi M, Wicks IP, Alexander WS, Mitsuuchi Y, Benetatos CA, Condon SM, Wong WW, Silke J, Vaux DL, Vince JE. Lawlor KE, et al. Among authors: masters sl. Nat Commun. 2015 Feb 18;6:6282. doi: 10.1038/ncomms7282. Nat Commun. 2015. PMID: 25693118 Free PMC article.
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.
Kim ML, Chae JJ, Park YH, De Nardo D, Stirzaker RA, Ko HJ, Tye H, Cengia L, DiRago L, Metcalf D, Roberts AW, Kastner DL, Lew AM, Lyras D, Kile BT, Croker BA, Masters SL. Kim ML, et al. Among authors: masters sl. J Exp Med. 2015 Jun 1;212(6):927-38. doi: 10.1084/jem.20142384. Epub 2015 May 25. J Exp Med. 2015. PMID: 26008898 Free PMC article.
IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.
Murphy AJ, Kraakman MJ, Kammoun HL, Dragoljevic D, Lee MK, Lawlor KE, Wentworth JM, Vasanthakumar A, Gerlic M, Whitehead LW, DiRago L, Cengia L, Lane RM, Metcalf D, Vince JE, Harrison LC, Kallies A, Kile BT, Croker BA, Febbraio MA, Masters SL. Murphy AJ, et al. Among authors: masters sl. Cell Metab. 2016 Jan 12;23(1):155-64. doi: 10.1016/j.cmet.2015.09.024. Epub 2015 Oct 22. Cell Metab. 2016. PMID: 26603191 Free article.
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation.
Pearson JS, Giogha C, Mühlen S, Nachbur U, Pham CL, Zhang Y, Hildebrand JM, Oates CV, Lung TW, Ingle D, Dagley LF, Bankovacki A, Petrie EJ, Schroeder GN, Crepin VF, Frankel G, Masters SL, Vince J, Murphy JM, Sunde M, Webb AI, Silke J, Hartland EL. Pearson JS, et al. Among authors: masters sl. Nat Microbiol. 2017 Jan 13;2:16258. doi: 10.1038/nmicrobiol.2016.258. Nat Microbiol. 2017. PMID: 28085133 Free PMC article.
167 results